Nicolet Laure, Viviano Manuela, Dickson Cheryl, Jeannot Emilien
Institute of Global Health, Faculty of Medicine, Chemin de Mines 9, 1202 Geneva, Switzerland.
Gynecology Division, Department of Obstetrics and Gynecology, Geneva University Hospitals, Boulevard de la Cluse 30, 1205 Geneva, Switzerland.
Vaccines (Basel). 2022 Apr 25;10(5):680. doi: 10.3390/vaccines10050680.
In Switzerland, HPV vaccination has been recommended since 2007 for all adolescent girls aged between 11 and 14 years. More than 10 years after the introduction of this recommendation, immunization coverage targets have not been met. Very few studies at a national level describe the reasons for the reluctance of some young women to become vaccinated. The aim of this study is to describe the socio-demographic characteristics of a population of vaccinated and unvaccinated female health students and then to compare the different factors that may have influenced their vaccine choice.
Female health students in the French-speaking part of Switzerland, aged between 18 and 31, were invited to participate in the study. A total of 234 female students completed a questionnaire that included questions about their socio-demographic data, sexual behavior and vaccination status.
69% of the participants received at least one dose of the vaccine. Women who had not yet had sex were less likely to be vaccinated than sexually active women (ORa: 0.1, 0.0-0.4, 95% CI), the same as those who did not express an opinion about the importance of vaccination (ORa: 0.1: 0.0-0.6, 95% CI). The main reasons given for refusing vaccination were fear of side effects (26.0%), parental opposition (24.6%) and reluctance of the attending physician (13.6%).
The main results of this study highlight a good rate of vaccine coverage in the sample population. Reasons for nonvaccination demonstrate the need to provide information on the vaccine to the target audience, as well as to parents and health professionals.
自2007年起，瑞士就建议所有11至14岁的青春期女孩接种人乳头瘤病毒（HPV）疫苗。在这项建议提出10多年后，免疫接种覆盖率目标仍未实现。在国家层面，很少有研究描述一些年轻女性不愿接种疫苗的原因。本研究的目的是描述已接种和未接种疫苗的女性医学生群体的社会人口特征，然后比较可能影响她们疫苗选择的不同因素。
邀请瑞士法语区年龄在18至31岁之间的女性医学生参与研究。共有234名女学生完成了一份问卷，其中包括有关她们的社会人口数据、性行为和疫苗接种状况的问题。
69%的参与者至少接种了一剂疫苗。尚未发生性行为的女性比有性行为的女性接种疫苗的可能性更小（优势比：0.1，0.0 - 0.4，95%置信区间），与那些对疫苗接种重要性未表达意见的女性情况相同（优势比：0.1：0.0 - 0.6，95%置信区间）。拒绝接种疫苗的主要原因是担心副作用（26.0%）、父母反对（24.6%）和主治医生的不情愿（13.6%）。
本研究的主要结果突出了样本人群中良好的疫苗接种率。未接种疫苗的原因表明有必要向目标受众以及父母和卫生专业人员提供有关疫苗的信息。
