Parraca Jose A, Rubio-Zarapuz Alejandro, Tornero-Aguilera José Francisco, Clemente-Suárez Vicente Javier, Tomas-Carus Pablo, Costa Ana Rodrigues
Departamento de Desporto e Saúde, Escola de Saúde e Desenvolvimento Humano, Universidade de Évora, 7004-516 Évora, Portugal.
Comprehensive Health Research Centre (CHRC), University of Évora, 7004-516 Évora, Portugal.
Int J Mol Sci. 2025 Jan 29;26(3):1164. doi: 10.3390/ijms26031164.
This study examines the biochemical profile of saliva, focusing on flow rate, total protein concentration, and the enzymatic activities of amylase and catalase. The study aims to explore the correlations between these parameters and their response to physiological stress induced by physical activity, providing insights into saliva's diagnostic potential. Thirty-one participants were recruited, and saliva samples were collected before and after a structured physical activity session. Biochemical parameters were analyzed using established protocols to assess changes induced by exercise. Significant positive correlations were observed between protein concentration and amylase activity, particularly in post-exercise conditions. No significant correlations were found between the salivary flow and enzyme activities. Catalase activity displayed a weaker association with protein levels. These findings suggest that saliva can be a non-invasive biomarker for systemic health and stress responses. The study highlights the diagnostic utility of saliva and underscores the need for further investigations in younger and healthier populations to broaden the applicability of these results.
本研究考察唾液的生化特征，重点关注流速、总蛋白浓度以及淀粉酶和过氧化氢酶的酶活性。该研究旨在探索这些参数之间的相关性以及它们对体育活动引起的生理应激的反应，从而深入了解唾液的诊断潜力。招募了31名参与者，并在有组织的体育活动前后收集唾液样本。使用既定方案分析生化参数，以评估运动引起的变化。在蛋白质浓度和淀粉酶活性之间观察到显著的正相关，尤其是在运动后的情况下。未发现唾液流速与酶活性之间存在显著相关性。过氧化氢酶活性与蛋白质水平的关联较弱。这些发现表明，唾液可以作为全身健康和应激反应的非侵入性生物标志物。该研究突出了唾液的诊断效用，并强调需要在更年轻、更健康的人群中进行进一步研究，以扩大这些结果的适用性。
