Arvan D, Shirey T L
Ann Clin Lab Sci. 1985 May-Jun;15(3):252-9.
A prototype KODAK EKTACHEM Clinical Chemistry Slide (BuBc) provided a measurement of serum conjugated bilirubin which was at least as sensitive to developing conjugated hyperbilirubinemia as values provided by a direct (diazo) bilirubin assay. Under conditions where the impairment of hepatobiliary excretion was relieved in patients being treated for various hepatobiliary diseases, conjugated bilirubin was cleared from serum more rapidly than alkaline phosphatase, the delta bilirubin fraction, and bilirubin measured by the direct and total bilirubin assays. It is concluded that the conjugated bilirubin measurement provided by the BuBc Slide appears to be an earlier indicator of relief from hepatobiliary cholestasis, or conversely of residual impairment, than direct bilirubin, total bilirubin, or alkaline phosphatase.
一款原型柯达 EKTACHEM 临床化学载玻片（BuBc）可对血清结合胆红素进行测量，其对于检测结合胆红素血症发展的敏感度至少与直接（重氮）胆红素测定法所提供的值相当。在接受各种肝胆疾病治疗的患者中，当肝胆排泄功能障碍得到缓解时，结合胆红素从血清中清除的速度比碱性磷酸酶、δ胆红素组分以及通过直接胆红素和总胆红素测定法测得的胆红素更快。得出的结论是，与直接胆红素、总胆红素或碱性磷酸酶相比，BuBc 载玻片提供的结合胆红素测量值似乎是肝胆胆汁淤积缓解或反之残余功能障碍的更早指标。
