Iijima Kazuyoshi, Mima Yoshihito
Department of Dermatology, Teikyo Mizonokuchi Hospital, Kanagawa, JPN.
Department of Dermatology, Tokyo Metropolitan Police Hospital, Tokyo, JPN.
Cureus. 2025 Jan 11;17(1):e77303. doi: 10.7759/cureus.77303. eCollection 2025 Jan.
Lichen sclerosus (LS) and morphea are chronic inflammatory disorders with overlapping clinical and histopathological features, often complicating diagnosis. While the co-occurrence of LS and morphea as distinct lesions in the same patient is well documented, their overlap within a single lesion is rare, especially in genital regions. Herein, we present a case of a 60-year-old female with coexisting LS and morphea in the genital region, exhibiting features of LS while demonstrating histological characteristics of both. This case underscores the diagnostic challenges and provides further support for the possibility that LS and morphea may represent varying manifestations within a shared disease spectrum.
硬化性苔藓（LS）和硬斑病是具有重叠临床和组织病理学特征的慢性炎症性疾病，常使诊断复杂化。虽然同一患者中LS和硬斑病作为不同病变同时出现已有充分记录，但它们在单个病变内的重叠情况罕见，尤其是在生殖器区域。在此，我们报告一例60岁女性，其生殖器区域同时存在LS和硬斑病，表现出LS的特征，同时具备两者的组织学特征。该病例强调了诊断挑战，并进一步支持了LS和硬斑病可能代表共同疾病谱内不同表现形式的可能性。
