Khatun Zakia, Kristinsdóttir Sara, Thóra Thórisdóttir Arndís, Björk Halldórsdóttir Linda, Tortorella Francesco, Gargiulo Paolo, Helgason Thordur
Department of Engineering, Institute of Biomedical and Neural Engineering, Reykjavik University, Reykjavik, Iceland.
Department of Information and Electrical Engineering and Applied Mathematics, University of Salerno, Salerno, Italy.
Front Neurol. 2025 Jan 30;15:1522121. doi: 10.3389/fneur.2024.1522121. eCollection 2024.
Patellar tendon reflex tests are essential for evaluating neuromuscular function and identifying abnormalities in nerve conduction and muscle response. This study explored how age, height, weight, and gender influence reflex response times in healthy individuals, providing a reference for future research on different neuromuscular conditions. We analyzed reflex onset, endpoint, and total duration of reflexes using electromyography (EMG) recordings from 40 healthy participants. Reflexes were elicited by striking the patellar tendon, and participants were grouped based on age, height, weight, and gender. We investigated both the individual and combined effects of these factors on reflex response times. Additionally, height and weight-normalized data were analyzed to clarify their roles in influencing reflexes across age groups. Gender-specific analyses were conducted as well to assess potential differences between males and females. Our findings indicated that reflex onset was significantly delayed in elderly individuals, particularly in taller and heavier individuals, and in males compared to females. Even with height normalization, elderly participants showed slower reflexes. Weight-normalized data revealed that younger participants exhibited longer total reflex durations, likely due to their greater height, which impacted nerve conduction time. This trend was consistent across genders, with males generally exhibiting longer duration of reflex response times. These findings provide insights into how different demographic factors, particularly aging, affect neuromuscular reflexes and could serve as a reference for diagnosing and monitoring neuromuscular disorders.
髌腱反射测试对于评估神经肌肉功能以及识别神经传导和肌肉反应异常至关重要。本研究探讨了年龄、身高、体重和性别如何影响健康个体的反射反应时间,为未来针对不同神经肌肉疾病的研究提供参考。我们使用40名健康参与者的肌电图(EMG)记录分析了反射的起始、终点和总持续时间。通过敲击髌腱引发反射,并根据年龄、身高、体重和性别对参与者进行分组。我们研究了这些因素对反射反应时间的个体影响和综合影响。此外,还分析了身高和体重标准化数据,以阐明它们在影响不同年龄组反射方面的作用。还进行了性别特异性分析,以评估男性和女性之间的潜在差异。我们的研究结果表明,老年人的反射起始明显延迟,特别是在身高较高、体重较重的个体以及男性中,与女性相比更为明显。即使进行了身高标准化,老年参与者的反射仍然较慢。体重标准化数据显示,年轻参与者的反射总持续时间较长,可能是由于他们较高的身高影响了神经传导时间。这种趋势在不同性别中是一致的,男性通常表现出较长的反射反应时间。这些发现为不同人口统计学因素,特别是衰老,如何影响神经肌肉反射提供了见解,并可为诊断和监测神经肌肉疾病提供参考。