Liu Yanlin, Hu Jun, Duan Xiaoli, Ding Wenlong, Xu Menglan, Xiong Yan
Synthetic Biology Center, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou, Fujian Province, China; email:
Fujian Provincial Key Laboratory of Haixia Applied Plant Systems Biology, College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, Fujian Province, China.
Annu Rev Plant Biol. 2025 May;76(1):341-371. doi: 10.1146/annurev-arplant-083123-050311. Epub 2025 Feb 14.
The target of rapamycin (TOR) is a central regulator of growth, development, and stress adaptation in plants. This review delves into the molecular intricacies of TOR signaling, highlighting its conservation and specificity across eukaryotic lineages. We explore the molecular architecture of TOR complexes, their regulation by a myriad of upstream signals, and their consequential impacts on plant physiology. The roles of TOR in orchestrating nutrient sensing, hormonal cues, and environmental signals are highlighted, illustrating its pivotal function in modulating plant growth and development. Furthermore, we examine the impact of TOR on plant responses to various biotic and abiotic stresses, underscoring its potential as a target for agricultural improvements. This synthesis of current knowledge on plant TOR signaling sheds light on the complex interplay between growth promotion and stress adaptation, offering a foundation for future research and applications in plant biology.
雷帕霉素靶蛋白（TOR）是植物生长、发育和胁迫适应的核心调节因子。本综述深入探讨了TOR信号传导的分子复杂性，强调了其在真核生物谱系中的保守性和特异性。我们探究了TOR复合物的分子结构、它们受众多上游信号的调控以及它们对植物生理学的相应影响。重点介绍了TOR在协调营养感知、激素信号和环境信号方面的作用，阐明了其在调节植物生长和发育中的关键功能。此外，我们研究了TOR对植物应对各种生物和非生物胁迫的影响，强调了其作为农业改良靶点的潜力。对植物TOR信号传导当前知识的综合阐述揭示了生长促进与胁迫适应之间的复杂相互作用，为植物生物学的未来研究和应用奠定了基础。
