Nyberg P, Adolfsson R, Hardy J A, Nordberg A, Wester P, Winblad B
Brain Res. 1985 Apr 29;333(1):139-42. doi: 10.1016/0006-8993(85)90133-7.
Analysis of catecholamine levels in postmortem human control and Alzheimer brains revealed lower mean concentrations of noradrenaline, but not dopamine, in nucleus caudatus, putamen and globus pallidus, but not in hippocampus, of the Alzheimer brains. Generally, noradrenaline levels were higher in the more posterior parts of nucleus caudatus and putamen in the control brains, whereas such gradients were absent in the Alzheimer brains.
对死后人类对照大脑和阿尔茨海默病大脑中的儿茶酚胺水平进行分析发现，在阿尔茨海默病大脑的尾状核、壳核和苍白球中，去甲肾上腺素的平均浓度较低，但多巴胺的平均浓度在海马体中未降低。一般来说，在对照大脑中，尾状核和壳核后部的去甲肾上腺素水平较高，而在阿尔茨海默病大脑中不存在这种梯度。
