年龄以及死亡与尸检之间的时间间隔对人类基底神经节中多巴胺和3-甲氧基酪胺水平的影响。
Influence of age and time interval between death and autopsy on dopamine and 3-methoxytyramine levels in human basal ganglia.
作者信息
Carlsson A, Winblad B
出版信息
J Neural Transm. 1976;38(3-4):271-6. doi: 10.1007/BF01249444.
PMID:956813
Abstract
The caudate nuclei and putamens of 30 human brains were analyzed for dopamine and its metabolite 3-methoxytyramine, most of which was presumably formed from dopamine postmortally. It was found that dopamine and the sum (dopamine + methoxytyramine) but not methoxytyramine declined with the time interval between death and autopsy as well as with age.
摘要
对30个成年人脑的尾状核和壳核进行了多巴胺及其代谢产物3-甲氧基酪胺的分析，其中大部分可能是死后由多巴胺形成的。研究发现，多巴胺及其总和（多巴胺+甲氧基酪胺）会随着死亡与尸检之间的时间间隔以及年龄的增长而下降，但甲氧基酪胺不会。
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