Wu Shasha, Sun Lei, Bian Yeping, Wu Fan, Shi Donghai, Xu Haijun
Jiangsu Co-innovation Center of Efficient Processing and Utilization of Forest Resources, College of Chemical Engineering, Key Laboratory of Forestry Genetics & Biotechnology of Ministry of Education, Nanjing Forestry University, Nanjing 210037 PR China.
Department of Intensive Care Unit, Geriatric Hospital of Nanjing Medical University, No. 30 Luojia Road, Nanjing 210024 PR China.
Spectrochim Acta A Mol Biomol Spectrosc. 2025 May 5;332:125748. doi: 10.1016/j.saa.2025.125748. Epub 2025 Jan 13.
In this study, a novel ratiometric fluorescent sensor SYW for the detection of BF was successfully synthesized based on imidazole-quinoline. The sensor showed noticeable fluorescence enhancement after binding to BF with remarkable color change observed by naked eye in a short response time (within 30 s). Additionally, the probe had an extremely low detection limit (1.71 nM) and exhibited excellent specificity for BF. The recognition mechanism of the probe SYW for BF was determined by F NMR, FTIR, HRMS, and density functional theory (DFT) calculations. Moreover, the probe can also be applied in quantitatively detecting BF concentrations as well as gaseous BF by test paper strips containing SYW. In addition, the probe SYW was also employed to detect BF in living cells. These results suggested that the probe SYW displayed promising applications in environmental monitoring, and industrial production, and biological systems.
在本研究中，基于咪唑 - 喹啉成功合成了一种用于检测硼氟化物（BF）的新型比率荧光传感器SYW。该传感器与BF结合后显示出明显的荧光增强，在短响应时间（30秒内）肉眼可观察到显著的颜色变化。此外，该探针具有极低的检测限（1.71 nM），并且对BF表现出优异的特异性。通过氟核磁共振（F NMR）、傅里叶变换红外光谱（FTIR）、高分辨率质谱（HRMS）和密度泛函理论（DFT）计算确定了探针SYW对BF的识别机制。此外，该探针还可通过含有SYW的试纸条用于定量检测BF浓度以及气态BF。此外，探针SYW还被用于检测活细胞中的BF。这些结果表明，探针SYW在环境监测、工业生产和生物系统中显示出有前景的应用。
