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克氏壶腹肿瘤——1例伴有肝转移的肝门部胆管癌病例报告。

Klatskin tumor - A case report of hilar cholangiocarcinoma with hepatic metastasis.

作者信息

Mirzaei Soheil, Motaghed Zahra, Shokri Shiva, Shafeghat Faride

机构信息

Department of Anatomy, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran; Department of Radiology, Shahid Sattari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Department of Radiology, Shahid Sattari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

出版信息

Int J Surg Case Rep. 2025 Mar;128:111051. doi: 10.1016/j.ijscr.2025.111051. Epub 2025 Feb 12.

Abstract

INTRODUCTION

Klatskin tumor is a malignant neoplasm originating at the hilum of the liver, where the right and left hepatic ducts converge. This tumor is a rare malignancy; given that most Klatskin tumors are unresectable at the time of diagnosis, the prognosis is very poor.

CASE PRESENTATION

We present a 58-year-old woman with severe jaundice. Imaging and laboratory findings were consistent with a diagnosis of Klatskin tumor. Given the advanced stage of the tumor, conservative management with percutaneous transhepatic cholangiography (PTC) was implemented to alleviate symptoms. However, due to the severity of the malignancy, The patient died.

CLINICAL DISCUSSION

The clinical and radiographic manifestations of Klatskin tumors might overlap with those of inflammatory, infectious, and vascular diseases, making differential diagnosis complex. Despite advancements in imaging techniques and the high accuracy of these modalities, the definitive diagnosis of Klatskin tumors remains very challenging in some cases.

CONCLUSION

Considering that Klatskin tumor is a rare and fatal malignancy, early diagnosis during the initial stages of the tumor is associated with a better prognosis and may make the malignancy resectable.

摘要

引言

肝门部胆管癌是一种起源于肝门的恶性肿瘤,左右肝管在此汇合。这种肿瘤是一种罕见的恶性肿瘤;鉴于大多数肝门部胆管癌在诊断时无法切除,预后非常差。

病例报告

我们报告一名58岁重度黄疸女性。影像学和实验室检查结果符合肝门部胆管癌的诊断。鉴于肿瘤处于晚期,实施了经皮肝穿刺胆管造影术(PTC)的保守治疗以缓解症状。然而,由于恶性程度高,患者死亡。

临床讨论

肝门部胆管癌的临床和影像学表现可能与炎症、感染和血管疾病的表现重叠,使得鉴别诊断复杂。尽管成像技术有所进步且这些检查方式准确性高,但在某些情况下,肝门部胆管癌的明确诊断仍然非常具有挑战性。

结论

鉴于肝门部胆管癌是一种罕见且致命的恶性肿瘤,在肿瘤早期进行早期诊断与较好的预后相关,并且可能使恶性肿瘤可切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3649/11872548/32dd96a1bd1b/gr1.jpg

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