Aly Salma, Chen Yuying, Ahmed Abdulaziz, Wen Huacong, Mehta Tapan
Department of Family and Community Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
Department of Physical Medicine and Rehabilitation, Spain Rehabilitation Center, University of Alabama at Birmingham, Birmingham, AL, USA.
Spinal Cord. 2025 Apr;63(4):214-221. doi: 10.1038/s41393-024-01055-9. Epub 2025 Feb 15.
Retrospective cohort study.
The primary aim was to develop a machine learning (ML) model to predict rehospitalization during the first year of traumatic spinal cord injury (TSCI) and to identify top predictors using data obtained during initial rehabilitation. The secondary aim was to predict prolonged hospital stay among the rehospitalized group.
Eighteen SCI Model Systems centers throughout the United States.
Data were retrieved from the National Spinal Cord Injury Model Systems Database. The participants were divided into 2 groups based on rehospitalization during the first year of injury. Those who experienced rehospitalization during first year were further grouped into prolonged stay (>75th quartile of the total length of stay) or non-prolonged stay. Variables considered in models included socio-demographic factors, clinical characteristics, and comorbidities.
The best performing classification models were Random Forest for predicting rehospitalization and Adaptive Boosting for prolonged stay. The most important predictors in both models were the degree of functional independence, American Spinal Injury Association (ASIA) scores, age, days from injury to rehabilitation admission and body mass index. Additionally, for prolonged stays, pressure injury as a reason for rehospitalization was top predictor.
Functional Independence Measure (FIM) and ASIA scores emerge as key predictors of both rehospitalizations and prolonged rehospitalizations. These findings may assist clinicians in patient risk assessment. Furthermore, the identification of pressure injury as a primary predictor for prolonged stays signifies a targeted focus on preventive measures for pressure injury-related rehospitalizations, offering a specific strategy to enhance patient care and outcomes.
回顾性队列研究。
主要目的是开发一种机器学习(ML)模型,以预测创伤性脊髓损伤(TSCI)第一年的再次住院情况,并使用初始康复期间获得的数据确定主要预测因素。次要目的是预测再次住院组的住院时间延长情况。
美国各地的18个脊髓损伤模型系统中心。
数据取自国家脊髓损伤模型系统数据库。根据受伤后第一年的再次住院情况将参与者分为两组。那些在第一年经历再次住院的患者进一步分为住院时间延长组(>住院总时长的第75四分位数)或非延长组。模型中考虑的变量包括社会人口统计学因素、临床特征和合并症。
预测再次住院的最佳分类模型是随机森林,预测住院时间延长的最佳分类模型是自适应增强。两个模型中最重要的预测因素是功能独立程度、美国脊髓损伤协会(ASIA)评分、年龄、受伤至康复入院天数和体重指数。此外,对于住院时间延长的情况,因压力性损伤再次住院是主要预测因素。
功能独立性评定量表(FIM)和ASIA评分是再次住院和再次住院时间延长的关键预测因素。这些发现可能有助于临床医生进行患者风险评估。此外,将压力性损伤确定为住院时间延长的主要预测因素,意味着有针对性地关注与压力性损伤相关的再次住院的预防措施,为提高患者护理质量和改善预后提供了具体策略。