Beyene Zerihun, Sium Abraham Fessehaye, Gebremedhin Genet, Dereje Bethel
Department of Obstetrics and Gynecology St. Paul's Hospital Millennium Medical College (SPHMMC) Addis Ababa Ethiopia.
Health Sci Rep. 2025 Feb 17;8(2):e70434. doi: 10.1002/hsr2.70434. eCollection 2025 Feb.
Screening for depression and understanding its predictors is essential as it can inform the type and extent of psychological intervention that needs to be provided before or during infertility treatment. This study aimed to determine the prevalence of depression and associated factors among infertile women who received care at a Center for Fertility and Reproductive Medicine (CFRM) in Ethiopia.
This was a cross-sectional study conducted at CFRM in St. Paul's Hospital Millennium Medical College (Ethiopia) on women with infertility over a period of 3 months, from November 11, 2019 to February 2020. Data were collected prospectively through face-to-face interviews with the study participants using PHQ-9. Data were analyzed using SPSS version 23. Simple descriptive statistics and bivariate and multivariate regression analysis were performed as appropriate. Frequency, percentage, adjusted odds ratio (AOR) along with 95% CI were used to present the finding.
A total of 381 infertile women were approached, and 32 women did not respond, constituting a repose rate of 91.6%. Among the 349 infertile women included in the final analysis, the prevalence of depression was found to be 42.1% (147/349). Low monthly income (AOR = 4.4, 95% CI, 1.3-14.5), unemployment (AOR = 4.3, 95% CI, 1.2-11.5), history of divorce (AOR = 4.4. 95% CI, 1.4-13.0), and partner's low level of education (AOR = 3.2, 95% CI, 1.2-8.9) were associated with detection of depression among the infertile women included in the study.
The prevalence of depression among infertile women is lower than reports from previous studies. Regardless of this relatively low prevalence, our study supports integration of depression screening and psychological treatment for those affected before and during infertility treatments, as a vital component of healthcare infertile women.
筛查抑郁症并了解其预测因素至关重要，因为这可以为在不孕治疗之前或期间需要提供的心理干预的类型和程度提供依据。本研究旨在确定在埃塞俄比亚一家生育与生殖医学中心（CFRM）接受治疗的不孕女性中抑郁症的患病率及相关因素。
这是一项在埃塞俄比亚圣保罗医院千禧医学院的CFRM对不孕女性进行的横断面研究，研究为期3个月，从2019年11月11日至2020年2月。通过使用PHQ-9对研究参与者进行面对面访谈前瞻性收集数据。使用SPSS 23版进行数据分析。酌情进行简单描述性统计以及双变量和多变量回归分析。使用频率、百分比、调整后的优势比（AOR）以及95%置信区间来呈现研究结果。
总共接触了381名不孕女性，32名女性未做出回应，回复率为91.6%。在最终分析纳入的349名不孕女性中，抑郁症患病率为42.1%（147/349）。月收入低（AOR = 4.4，95%置信区间，1.3 - 14.5）、失业（AOR = 4.3，95%置信区间，1.2 - 11.5）、离婚史（AOR = 4.4，95%置信区间，1.4 - 13.0）以及伴侣受教育程度低（AOR = 3.2，95%置信区间，1.2 - 8.9）与研究中纳入的不孕女性抑郁症的检出相关。
不孕女性中抑郁症的患病率低于先前研究报告。尽管患病率相对较低，但我们的研究支持将抑郁症筛查和对受影响者在不孕治疗之前及期间的心理治疗作为不孕女性医疗保健的重要组成部分进行整合。
