Scadding G K, Conti D M, Scheire S, Backer V, Blaiss M, Cardell L O, De Yun W, Ellis A K, Fokkens W, Fox A T, Gilbert Kruz T, Halken S, Hellings P W, Hox V, Kalogjera L, Lau S, Marinho S, McDonald M, Mösges R, Mullol J, Nasser S, Pawankar R, Price D, Ryan D, Scadding G, Smith P, Sosa Kostrábová M, Vazquez-Ortiz M, Wahn U, Zhang L, Gevaert P
Royal National ENT Hospital and University College, London, United Kingdom.
Escuela de Doctorado UAM, Centro de Estudios de Posgrado, Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, no. 2, Ciudad Universitaria de Cantoblanco, Madrid, Spain.
Front Allergy. 2025 Feb 3;5:1531788. doi: 10.3389/falgy.2024.1531788. eCollection 2024.
Allergic rhinitis (AR), the most prevalent immunological disease, affects approximately 400 million individuals globally and can significantly impact quality of life (QoL). Despite nearly 25 years of guidelines, AR remains largely under- diagnosed, suboptimally treated and poorly controlled. In the light of new knowledge and treatment options, there is a necessity to update or revise fundamental AR definitions to facilitate communication across diverse specialties engaged in its treatment and to improve patient care. The European Forum for Research and Education in Allergy and Airway Diseases (EUFOREA) convened a meeting of experts and patient representatives to deliberate the optimal methodology for measuring AR treatment responses and establishing novel treatment goals. This paper presents a consensus on revised AR definitions, including control, severe allergic rhinoconjunctivitis (SARC), refractory severe allergic rhinoconjunctivitis (R-SARC), remission, resolution, improvement, exacerbation, treatable traits (TTs), treat to target, relapse, progression, disease modification, and prevention.
变应性鼻炎(AR)是最常见的免疫性疾病,全球约有4亿人受其影响,且会对生活质量(QoL)产生重大影响。尽管有近25年的指南,但AR在很大程度上仍存在诊断不足、治疗不充分和控制不佳的情况。鉴于新知识和治疗选择,有必要更新或修订AR的基本定义,以促进参与其治疗的不同专业之间的沟通,并改善患者护理。欧洲变应性疾病和气道疾病研究与教育论坛(EUFOREA)召开了一次专家和患者代表会议,以商讨测量AR治疗反应和确立新治疗目标的最佳方法。本文提出了关于修订后的AR定义的共识,包括控制、重度变应性鼻结膜炎(SARC)、难治性重度变应性鼻结膜炎(R-SARC)、缓解、消退、改善、加重、可治疗特征(TTs)、达标治疗、复发、进展、疾病改善和预防。