Suzuki O, Matsumoto T
Experientia. 1985 May 15;41(5):634-6. doi: 10.1007/BF02007695.
Both normetanephrine and metanephrine were found to be oxidized by both types of monoamine oxidase in mouse liver mitochondria. Both Km and Vmax values of type B MAO for both substrates were higher than those of type A MAO, which caused the shift of inhibition curves with clorgyline and deprenyl according to the increase in substrate concentration.
在小鼠肝线粒体中,去甲变肾上腺素和变肾上腺素均可被两种类型的单胺氧化酶氧化。两种底物的B型单胺氧化酶的Km值和Vmax值均高于A型单胺氧化酶,这导致随着底物浓度的增加,氯吉兰和司来吉兰的抑制曲线发生偏移。