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使用移动应用程序提高艾滋病毒感染者抗逆转录病毒疗法的依从性:一项纵向试点研究。

Using a mobile application for antiretroviral therapy adherence in people living with HIV: A longitudinal pilot study.

作者信息

Caetani Rejane, Wiechmann Susana L, Brancher Jacques D, Oliveira Vitor H F, Deminice Rafael

机构信息

Health Sciences Center, State University of Londrina, Londrina, Brazil.

Department of Clinical Medicine, State University of Londrina, Londrina, Brazil.

出版信息

South Afr J HIV Med. 2025 Jan 31;26(1):1646. doi: 10.4102/sajhivmed.v26i1.1646. eCollection 2025.

Abstract

BACKGROUND

The success of HIV treatment hinges on consistent adherence to antiretroviral therapy (ART).

OBJECTIVES

To conduct a longitudinal pilot study to assess the feasibility, acceptability and effectiveness of a mobile app to improve ART adherence.

METHOD

This study included adults living with HIV and using ART, who were allocated into two groups according to their willingness to use the app: users of the mobile application for ART management (Mobile) and non-users (Control). The application was developed by the researchers, and uses an alarm system to record ART use. Adherence was also assessed using the '' (CEAT-VIH) and the Multi-Method Tool questionnaire. Another questionnaire was administered to application users to assess acceptability. After 90 days, all the questionnaires were reapplied.

RESULTS

A significant difference in adherence was observed between the Mobile and Control groups ( = 0.04), but there was no significant difference in time ( = 0.2) or interaction ( = 0.5).

CONCLUSION

The application was not effective in improving ART adherence and showed low viability, but was considered acceptable among the participants.

摘要

背景

艾滋病病毒治疗的成功取决于对抗逆转录病毒疗法(ART)的持续坚持。

目的

开展一项纵向试点研究,以评估一款用于提高ART依从性的移动应用程序的可行性、可接受性和有效性。

方法

本研究纳入了正在接受ART治疗的成年艾滋病病毒感染者,根据他们使用该应用程序的意愿将其分为两组:ART管理移动应用程序用户(移动组)和非用户(对照组)。该应用程序由研究人员开发,使用警报系统记录ART使用情况。还使用“艾滋病病毒治疗依从性综合评估工具”(CEAT-VIH)和多方法工具问卷评估依从性。向应用程序用户发放了另一份问卷以评估可接受性。90天后,重新发放所有问卷。

结果

移动组和对照组在依从性方面存在显著差异(P = 0.04),但在时间方面(P = 0.2)或交互作用方面(P = 0.5)无显著差异。

结论

该应用程序在提高ART依从性方面无效,且可行性较低,但在参与者中被认为是可接受的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/95f9/11830866/4807d3594f13/HIVMED-26-1646-g001.jpg

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