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浅表皮肤溃疡作为系统性红斑狼疮的初始表现

Superficial Skin Ulcers as an Initial Manifestation of Systemic Lupus Erythematosus.

作者信息

Santacruz Juan Camilo, Mantilla Marta Juliana, Pulido Sandra, Bocanegra-Oyola Natalia, Londoño Juan Diego, Agudelo Carlos

机构信息

Rheumatology Department, Spondyloarthropathies Research Group, Universidad de la Sabana, Chía, COL.

Rheumatology Department, Centro De Investigación En Reumatología Y Especialidades Médicas (CIREEM), Bogotá, COL.

出版信息

Cureus. 2025 Jan 20;17(1):e77701. doi: 10.7759/cureus.77701. eCollection 2025 Jan.

Abstract

Cutaneous vasculitis is frequently present in patients with systemic lupus erythematosus (SLE), rheumatoid arthritis, and Sjögren's syndrome and is less common in dermatomyositis, systemic sclerosis, and relapsing polychondritis. Given the low prevalence of vasculitic involvement in this disease, the skin lesions described so far have had minimal semiological characterization. This has limited the provision of clear guidelines regarding their treatment, with most therapeutic interventions being extrapolated from idiopathic chronic leukocytoclastic vasculitis. We present the case of a female patient in her fifth decade of life who presented with superficial skin ulcers on the forearms as an initial manifestation, due to vasculitic involvement of small vessels secondary to SLE.

摘要

皮肤血管炎在系统性红斑狼疮(SLE)、类风湿关节炎和干燥综合征患者中经常出现,而在皮肌炎、系统性硬化症和复发性多软骨炎中则较少见。鉴于血管炎在该疾病中的患病率较低,迄今为止所描述的皮肤病变的症状学特征极少。这限制了关于其治疗的明确指南的提供,大多数治疗干预措施是从特发性慢性白细胞破碎性血管炎推断而来的。我们报告了一例50多岁的女性患者,其最初表现为前臂出现浅表性皮肤溃疡,这是由系统性红斑狼疮继发的小血管血管炎所致。

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