全球健康中的脓毒症：当前对抗脓毒症的全球战略
Sepsis in Global Health: Current global strategies to fight against sepsis.
作者信息
Saito Hiroki
机构信息
Interdeparmental Division of Critical Care Medicine University of Toronto Toronto Ontario Canada.
Depeartment of Emergency and Critical Care Medicine St. Marianna University School of Medicine Kawasaki Japan.
出版信息
Acute Med Surg. 2025 Feb 19;12(1):e70045. doi: 10.1002/ams2.70045. eCollection 2025 Jan-Dec.
Abstract
Sepsis is prevalent globally, causing a significant disease burden in global health. Sepsis is a complex disease condition, and therefore, the effective strategies to overcome sepsis need to be set up in layers across different sectors and populations. Over the years, the global society has been making progress in addressing sepsis as a public health threat. This review aims to examine and describe the current sepsis strategies globally and to sustain the fight against sepsis in the context of global health.
摘要
脓毒症在全球范围内普遍存在，给全球健康带来了重大疾病负担。脓毒症是一种复杂的病症，因此，需要在不同部门和人群中分层建立克服脓毒症的有效策略。多年来，全球社会在应对脓毒症这一公共卫生威胁方面一直在取得进展。本综述旨在审视和描述全球当前的脓毒症应对策略，并在全球健康背景下持续开展抗击脓毒症的斗争。
相似文献
1
Sepsis in Global Health: Current global strategies to fight against sepsis.全球健康中的脓毒症：当前对抗脓毒症的全球战略
Acute Med Surg. 2025 Feb 19;12(1):e70045. doi: 10.1002/ams2.70045. eCollection 2025 Jan-Dec.
2
Global mortality associated with 33 bacterial pathogens in 2019: a systematic analysis for the Global Burden of Disease Study 2019.2019 年与 33 种细菌病原体相关的全球死亡率：2019 年全球疾病负担研究的系统分析。
Lancet. 2022 Dec 17;400(10369):2221-2248. doi: 10.1016/S0140-6736(22)02185-7. Epub 2022 Nov 21.
3
Sepsis Care Pathway 2019.2019年脓毒症护理路径
Qatar Med J. 2019 Nov 7;2019(2):4. doi: 10.5339/qmj.2019.qccc.4. eCollection 2019.
4
Sepsis as a global health problem-why we need a global sepsis alliance.脓毒症作为一个全球性健康问题——为什么我们需要一个全球脓毒症联盟。
Shock. 2013 May;39 Suppl 1:3-4. doi: 10.1097/SHK.0b013e31828fad61.
5
The 2023 Latin America report of the Countdown on health and climate change: the imperative for health-centred climate-resilient development.《2023年健康与气候变化倒计时拉丁美洲报告：以健康为中心的气候适应型发展的必要性》
Lancet Reg Health Am. 2024 Apr 23;33:100746. doi: 10.1016/j.lana.2024.100746. eCollection 2024 May.
6
The global burden of sepsis: barriers and potential solutions.全球脓毒症负担：障碍与潜在解决方案。
Crit Care. 2018 Sep 23;22(1):232. doi: 10.1186/s13054-018-2157-z.
7
The Minderoo-Monaco Commission on Plastics and Human Health.美诺集团-摩纳哥基金会塑料与人体健康委员会
Ann Glob Health. 2023 Mar 21;89(1):23. doi: 10.5334/aogh.4056. eCollection 2023.
8
Global, regional, and national burden of neonatal sepsis and other neonatal infections, 1990-2019: findings from the Global Burden of Disease Study 2019.全球、区域和国家新生儿败血症和其他新生儿感染负担，1990-2019 年：2019 年全球疾病负担研究的结果。
Eur J Pediatr. 2023 May;182(5):2335-2343. doi: 10.1007/s00431-023-04911-7. Epub 2023 Mar 7.
9
Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 countries and territories and 811 subnational locations, 1990-2021: a systematic analysis for the Global Burden of Disease Study 2021.全球疾病、伤害和危险因素负担研究 2021 年，1990-2021 年全球 204 个国家和地区及 811 个次国家地区 371 种疾病和伤害的发病率、患病率、伤残损失生命年（YLDs）、伤残调整生命年（DALYs）以及健康期望寿命（HALE）：系统分析
Lancet. 2024 May 18;403(10440):2133-2161. doi: 10.1016/S0140-6736(24)00757-8. Epub 2024 Apr 17.
10
Sepsis in Aging Populations: A Review of Risk Factors, Diagnosis, and Management.老年人群中的脓毒症：危险因素、诊断及管理综述
Cureus. 2024 Dec 2;16(12):e74973. doi: 10.7759/cureus.74973. eCollection 2024 Dec.
引用本文的文献
1
Intestinal injury signaling pathway in sepsis.脓毒症中的肠道损伤信号通路。
Front Immunol. 2025 Jun 27;16:1620965. doi: 10.3389/fimmu.2025.1620965. eCollection 2025.
2
Inhibiting cathepsin B alleviates acute lung injury caused by sepsis through suppression of pyroptosis in lung epithelial cells.抑制组织蛋白酶B可通过抑制肺上皮细胞焦亡减轻脓毒症所致的急性肺损伤。
Eur J Med Res. 2025 May 20;30(1):403. doi: 10.1186/s40001-025-02679-0.
本文引用的文献
1
World leaders commit to reduce deaths from antimicrobial resistance by 10% by 2030.世界各国领导人承诺到2030年将抗菌药物耐药性导致的死亡人数减少10%。
BMJ. 2024 Sep 27;386:q2122. doi: 10.1136/bmj.q2122.
2
Immune Modulation in Sepsis, ARDS, and Covid-19 - The Road Traveled and the Road Ahead.脓毒症、ARDS 和 COVID-19 中的免疫调节：走过的路和前方的路。
NEJM Evid. 2022 Nov;1(11):EVIDra2200118. doi: 10.1056/EVIDra2200118. Epub 2022 Oct 25.
3
International Consensus Criteria for Pediatric Sepsis and Septic Shock.国际儿童脓毒症和脓毒性休克共识标准。
JAMA. 2024 Feb 27;331(8):665-674. doi: 10.1001/jama.2024.0179.
4
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes.揭示脓毒症的异质性：亚表型的比较分析。
Intensive Care Med. 2023 Nov;49(11):1360-1369. doi: 10.1007/s00134-023-07239-w. Epub 2023 Oct 18.
5
Identification of risk factors for post-intensive care syndrome in family members (PICS-F) among adult patients: a systematic review.识别成年患者重症监护后综合征患者家属（PICS-F）的风险因素：系统评价。
Anaesthesiol Intensive Ther. 2023;55(3):168-178. doi: 10.5114/ait.2023.130831.
6
Considerations for patient and public involvement and engagement in health research.考虑患者和公众在健康研究中的参与和投入。
Nat Med. 2023 Aug;29(8):1922-1929. doi: 10.1038/s41591-023-02445-x. Epub 2023 Jul 20.
7
Post-intensive care syndrome (PICS): recent updates.重症监护后综合征（PICS）：近期进展
J Intensive Care. 2023 May 23;11(1):23. doi: 10.1186/s40560-023-00670-7.
8
An analysis of existing national action plans for antimicrobial resistance-gaps and opportunities in strategies optimising antibiotic use in human populations.对现有的国家抗菌素耐药行动计划的分析——在优化人群中抗生素使用的策略方面存在的差距和机遇。
Lancet Glob Health. 2023 Mar;11(3):e466-e474. doi: 10.1016/S2214-109X(23)00019-0. Epub 2023 Feb 2.
9
How sepsis parallels and differs from COVID-19.脓毒症与新冠肺炎的异同。
EBioMedicine. 2022 Dec;86:104355. doi: 10.1016/j.ebiom.2022.104355. Epub 2022 Dec 2.
10
Clinical sepsis phenotypes in critically ill COVID-19 patients.危重症 COVID-19 患者的临床脓毒症表型。
Crit Care. 2022 Aug 9;26(1):244. doi: 10.1186/s13054-022-04118-6.
Zotero 插件