Rokan Nadia, Reddy Deepika
King's College Hospital NHS Foundation Trust London UK.
Guy's and St Thomas' NHS Foundation Trust London UK.
BJUI Compass. 2025 Feb 20;6(2):e70000. doi: 10.1002/bco2.70000. eCollection 2025 Feb.
Prostate cancer is a significant health issue in the United Kingdom, with rising incidence rates prompting the exploration of innovative treatment options. Focal therapy has emerged as a targeted approach that aims to treat localised prostate cancer while minimising damage to surrounding healthy tissue and subsequent adverse side effects. Focal therapy is National Institute for Health and Care Excellence (NICE)-approved treatment modality for patients with intermediate-risk localised prostate cancer. This is an evolving field, reflecting the rapidly improved understanding of both the trajectory patients face following a diagnosis of prostate cancer, and how best to apply ablative techniques. In this narrative review, we evaluate the historical development, current practices, clinical outcome reported in UK-based studies, and future directions of focal therapy for prostate cancer in the United Kingdom, highlighting its evolution as a viable treatment option.
前列腺癌是英国一个重大的健康问题，发病率不断上升促使人们探索创新的治疗方案。聚焦治疗已成为一种靶向治疗方法，旨在治疗局限性前列腺癌，同时将对周围健康组织的损害及后续不良副作用降至最低。聚焦治疗是英国国家卫生与临床优化研究所（NICE）批准的用于治疗中危局限性前列腺癌患者的治疗方式。这是一个不断发展的领域，反映出人们对前列腺癌诊断后患者所面临的病程以及如何最佳应用消融技术的理解迅速加深。在这篇叙述性综述中，我们评估了英国前列腺癌聚焦治疗的历史发展、当前实践、英国研究报告的临床结果以及未来方向，突出了其作为一种可行治疗选择的演变过程。
