Mhelembe Talani, Ramroop Shaun, Habyarimana Faustin
School of Mathematics, Statistics, and Computer Science, University of Kwazulu-Natal, Private Bag X01, PietermaritzburgScottsville, 3209, South Africa.
Malar J. 2025 Feb 21;24(1):55. doi: 10.1186/s12936-025-05289-7.
The study focused on the full population of children from Nigeria, where the dataset was obtained from the demographic and health surveys (DHS). About 10245 children were selected for the current study and based on the rapid diagnostic test (RDT) results, there is about 37% prevalence of malaria in children under 5 years old in Nigeria. Malaria is the leading public health concern, that contributes to child mortality in the African region.
The Nigeria Malaria Indicator Survey (NMIS) 2021 was utilized in this investigation. For the 2021 NMIS, a two-stage sampling technique was used. According to the NIMS study, the children chosen for anaemia and RDT testing were under 5 years of age.
A generalized linear mixed model (GLMM) was used to examine malaria RDT findings in conjunction with demographic, geographic, and socioeconomic characteristics. The following underlying risk factors for malaria in children were discovered in the study: altitude, anaemia level, age in months, fever status in the past 2 weeks, toilet facility, main wall material, main roof material, household wealth index, type of place of residence, sex of the child, mother's education level, and knowledge of the preventative measures that can be used to prevent malaria.
Missing data were not deleted in this investigation; instead, multiple imputations utilizing chained equations were used to approximate the missing observation. Based on the results found by using the GLMM, the findings of this study may influence how the government combats malaria in Nigeria. The novelty of this study is that the missing values were not dropped. However, imputation techniques were explored, and multiple imputation by chained equations was used.
该研究聚焦于来自尼日利亚的全体儿童群体,数据集取自人口与健康调查(DHS)。本研究选取了约10245名儿童,根据快速诊断检测(RDT)结果,尼日利亚5岁以下儿童的疟疾患病率约为37%。疟疾是主要的公共卫生问题,是导致非洲地区儿童死亡的原因之一。
本调查采用了2021年尼日利亚疟疾指标调查(NMIS)。对于2021年的NMIS,采用了两阶段抽样技术。根据NIMS研究,被选作贫血和RDT检测的儿童年龄在5岁以下。
使用广义线性混合模型(GLMM)结合人口统计学、地理和社会经济特征来检验疟疾RDT结果。该研究发现了以下儿童疟疾的潜在风险因素:海拔、贫血水平、月龄、过去2周的发热状况、厕所设施、主要墙体材料、主要屋顶材料、家庭财富指数、居住地点类型、儿童性别、母亲教育水平以及对可用于预防疟疾的预防措施的了解。
本调查未删除缺失数据;相反,使用链式方程的多重插补法来近似缺失观测值。基于使用GLMM得出的结果,本研究的发现可能会影响尼日利亚政府抗击疟疾的方式。本研究的新颖之处在于未舍弃缺失值。然而,探索了插补技术,并使用了链式方程多重插补法。