Gaston Rugiranka Tony, Ramroop Shaun
School of Mathematics, Statistics and Computer Sciences, University of KwaZulu-Natal, Pietermaritzburg Campus, Private Bag X01, Scottsville, 3209, South Africa.
Heliyon. 2020 May 13;6(5):e03946. doi: 10.1016/j.heliyon.2020.e03946. eCollection 2020 May.
Malaria remains a public health problem in developing countries and Malawi is no different. Although there has been an improvement in reducing malaria in Malawi, it remains a problem, especially in children less than five years old. The primary objective of the study was to assess whether socio-economic, geographic and demographic factors are associated with malaria, using the generalized additive mixed model (GAMM).
The study used a 2017 dataset from the Malawi Malaria Indicator Survey (MMI) with a total number of 2724 children under five years old. The study also utilized the GAMM to analyze data. The outcome was that either the child had malaria or did not, as detected using the malaria Rapid Diagnostic Test (RDT) (Ayele et al., 2014a).
In this study, more than 37 % of the total number of children who were tested showed a positive malaria result. In addition, the results from this study using GAMM indicated that anaemia, mother's education level, wealth index, child's age, the altitude of the place of residence, region, place of residence, toilet facility and electricity were significantly associated with a positive malaria RDT.
The study revealed that socio-economic, geographical and demographic variables are the key factors in improving malaria vectors in children. Improving income levels and supporting the poorer rural community mostly from the Central Region would be a great achievement in reducing malaria vectors in Malawi. In addition, improving health care in rural areas, especially at higher altitudes, would contribute to controlling malaria and reducing anaemia.
疟疾在发展中国家仍然是一个公共卫生问题,马拉维也不例外。尽管马拉维在减少疟疾方面有所改善,但它仍然是一个问题,尤其是在五岁以下的儿童中。本研究的主要目的是使用广义相加混合模型(GAMM)评估社会经济、地理和人口因素是否与疟疾有关。
该研究使用了2017年马拉维疟疾指标调查(MMI)的数据集,共有2724名五岁以下儿童。该研究还利用GAMM分析数据。结果是,使用疟疾快速诊断测试(RDT)检测出儿童是否感染疟疾(阿耶勒等人,2014年a)。
在本研究中,接受检测的儿童总数中超过37%的疟疾检测结果呈阳性。此外,本研究使用GAMM的结果表明,贫血、母亲的教育水平、财富指数、儿童年龄、居住地点的海拔高度、地区、居住地点、厕所设施和电力与疟疾RDT阳性显著相关。
该研究表明,社会经济、地理和人口变量是改善儿童疟疾传播媒介的关键因素。提高收入水平并支持主要来自中部地区的较贫困农村社区,将是马拉维减少疟疾传播媒介的一项重大成就。此外,改善农村地区的医疗保健,尤其是在高海拔地区,将有助于控制疟疾和减少贫血。