Archana P K, Vasudevan Suni, Panicker Unnikrishnan Gopalakrishna
Department of Chemistry, National Institute of Technology Calicut, 673601, Calicut, Kerala, India.
J Fluoresc. 2025 Feb 22. doi: 10.1007/s10895-025-04144-x.
Fluorescent sensing technologies have emerged as powerful tools in analytical science, offering exceptional sensitivity and selectivity for detecting a wide range of analytes. Among the advanced materials driving these technologies, quantum dots (QDs) and metal nanoparticles (MNPs) stand out due to their unique optical and electronic properties. When combined, these materials exhibit synergistic interactions those significantly enhance the fluorescence signals, enable efficient quenching, and offer tunable optical properties. This review explores the various protocols involved in the development, characterization, and performance evaluation of metal-QD composites; typically, metal-enhanced fluorescence (MEF) and Förster resonance energy transfer (FRET). The applications of the materials in the domain of biomedical diagnostics, environmental monitoring, and biosensing have been highlighted. The review also discusses the current challenges and future scope in the field of metal-QD-based fluorescent sensors and their possible transformative impact on next-generation sensing technologies.
荧光传感技术已成为分析科学中的强大工具，在检测多种分析物方面具有卓越的灵敏度和选择性。在推动这些技术发展的先进材料中，量子点（QDs）和金属纳米颗粒（MNPs）因其独特的光学和电子特性而脱颖而出。当这些材料结合时，它们会表现出协同相互作用，显著增强荧光信号、实现高效猝灭并提供可调谐的光学特性。本综述探讨了金属-量子点复合材料的开发、表征和性能评估所涉及的各种方案；通常包括金属增强荧光（MEF）和福斯特共振能量转移（FRET）。重点介绍了这些材料在生物医学诊断、环境监测和生物传感领域的应用。本综述还讨论了基于金属-量子点的荧光传感器领域当前面临的挑战和未来发展前景，以及它们对下一代传感技术可能产生的变革性影响。
