Degre Kendrick Chloe, Pusti Dibyendu, Yoon Geunyoung
College of Optometry, University of Houston, Houston, TX, United States.
Front Med (Lausanne). 2025 Feb 10;12:1496210. doi: 10.3389/fmed.2025.1496210. eCollection 2025.
The goal of this study is to characterize peripheral blur anisotropy resulting from monochromatic and chromatic aberrations along multiple meridians of myopic and emmetropic eyes using a newly developed quantitative metric.
A scanning Shack-Hartmann-based wavefront sensor was used to measure lower- and higher-order monochromatic aberrations along the horizontal and vertical meridians of 20 healthy adult subjects (10 myopes, and 10 emmetropes). Monochromatic and polychromatic blur asymmetry magnitude and orientation were quantified using a novel metric based on the optical transfer function. Published population averages of longitudinal and transverse chromatic aberration were used for polychromatic blur asymmetry calculations.
Blur anisotropy magnitude and orientation differed between refractive groups at several peripheral retinal locations under monochromatic and polychromatic conditions. Myopes were significantly more likely to have vertically oriented blur than emmetropes under monochromatic conditions in the temporal peripheral retina beyond 20°. These differences were minimized when chromatic aberrations were included, though the trend remained the same.
A trend of more vertical optical blur in the temporal periphery of myopes strengthens the hypothesis that myopes experience different peripheral optical blur than emmetropes, though the small sample size of the current study limits generalizability of the results. A thorough account of peripheral blur across the visual field may lead to a better understanding of the cues that the peripheral visual system might rely on during processes such as accommodation, emmetropization, and myopization.
本研究的目的是使用一种新开发的定量指标，来描述近视和正视眼沿多条子午线的单色和色差引起的周边模糊各向异性。
使用基于扫描夏克-哈特曼的波前传感器测量20名健康成年受试者（10名近视者和10名正视者）水平和垂直子午线上的低阶和高阶单色像差。使用基于光学传递函数的新指标对单色和多色模糊不对称的大小和方向进行量化。纵向和横向色差的已发表人群平均值用于多色模糊不对称计算。
在单色和多色条件下，不同屈光组在几个周边视网膜位置的模糊各向异性大小和方向存在差异。在单色条件下，近视者在颞侧周边视网膜超过20°处比正视者更有可能出现垂直方向的模糊。当纳入色差时，这些差异最小化，尽管趋势保持不变。
近视者颞侧周边更垂直的光学模糊趋势强化了这样一种假设，即近视者与正视者经历不同的周边光学模糊，尽管本研究的小样本量限制了结果的普遍性。全面了解整个视野的周边模糊可能有助于更好地理解周边视觉系统在诸如调节、正视化和近视化等过程中可能依赖的线索。
