Pontillo Martina, Trio Rossella, Rocco Nicola, Cinquerrui Ada, Di Lorenzo Mariana, Catanuto Giuseppe, Magnoni Francesca, Calenda Fabrizia, Castiello Carlo Luigi Junior, Ingenito Mafalda, Margherita Alessia Luciana, Velotti Nunzio, Musella Mario
Department of Advanced Biomedical Sciences, University of Naples "Federico II", 80131 Naples, Italy.
Breast Unit, University Hospital Federico II, 80131 Naples, Italy.
Healthcare (Basel). 2025 Feb 13;13(4):407. doi: 10.3390/healthcare13040407.
Breast cancer remains the most prevalent malignancy among women worldwide, necessitating effective prevention strategies. The current literature was scrutinized to investigate the impact of dietary factors, such as the consumption of fruits, vegetables, and whole grains, and dietary patterns such as the Mediterranean diet on reducing the risk of breast cancer. Additionally, the potential role of diet in diminishing the risk of disease recurrence and enhancing outcomes among breast cancer survivors was explored. : A systematic literature search was conducted using PubMed, Web of Science, Scopus, and EMBASE to identify relevant studies published between 2000 and 2024. Inclusion criteria were applied to select studies with robust methodologies, including randomized clinical trials, meta-analyses, and prospective cohort studies focusing on adult women. Only studies published in English were considered. Papers on animal studies, editorials, and case series were excluded. : Our findings show the critical interplay between diet and breast cancer prevention, crucial for the development of effective strategies to both primary and tertiary prevention. Challenges such as adherence to dietary recommendations, cultural and socioeconomic disparities, and limited high-quality evidence were identified. : This review underscores the critical need to integrate nutrition into clinical practice and highlights avenues for future research, including personalized dietary interventions.
乳腺癌仍然是全球女性中最常见的恶性肿瘤,因此需要有效的预防策略。对当前文献进行了审查,以研究饮食因素(如水果、蔬菜和全谷物的摄入量)以及地中海饮食等饮食模式对降低乳腺癌风险的影响。此外,还探讨了饮食在降低乳腺癌幸存者疾病复发风险和改善预后方面的潜在作用。:使用PubMed、科学网、Scopus和EMBASE进行了系统的文献检索,以识别2000年至2024年期间发表的相关研究。应用纳入标准选择方法可靠的研究,包括随机临床试验、荟萃分析以及针对成年女性的前瞻性队列研究。仅考虑以英文发表的研究。排除了关于动物研究、社论和病例系列的论文。:我们的研究结果表明饮食与乳腺癌预防之间存在关键的相互作用,这对于制定有效的一级和三级预防策略至关重要。确定了诸如遵守饮食建议、文化和社会经济差异以及高质量证据有限等挑战。:本综述强调了将营养纳入临床实践的迫切需求,并突出了未来研究的方向,包括个性化饮食干预。