Baudart Clara, Briot Thomas
Hospices Civils de Lyon, Groupement Hospitalier Nord, Pharmacy Department, 69317 Lyon, France.
LAGEPP, CNRS UMR5007, Université Claude Bernard Lyon 1, 69622 Villeurbanne, France.
Pharmacy (Basel). 2025 Jan 25;13(1):9. doi: 10.3390/pharmacy13010009.
The COVID-19 pandemic led to a major interest in ultraviolet C (UVC) disinfection devices and accelerated the implementation of UVC devices in healthcare facilities due to their proven efficacy in the inactivation of various pathogens. While UVC technology offers several advantages, some drawbacks remain. This report, drawing on studies, guidelines, and practical experiences related to the use of UVC technology in healthcare settings, examines the efficacy, advantages, and drawbacks of UVC devices, and their applications in aseptic drug-compounding pharmaceutical units.
Studies, guidelines, and practical experiences were selected. UVC technology offers advantages such as rapid disinfection, reduced reliance on chemical agents, minimal waste, and freedom from manual disinfection variability, making it particularly valuable for maintaining aseptic conditions in compounding environments. However, some drawbacks persist, as it is a germ-dependent method and there is currently no standardized method for ensuring effectiveness.
This opinion paper highlights the effectiveness of UCV technology in pharmaceutical compounding units, proving that it is a viable alternative to the traditionally used manual and operator-dependent methods. However, there is a need for standardized methods to evaluate UVC devices.
由于新冠疫情,紫外线C(UVC)消毒设备引发了广泛关注,且因其在灭活各种病原体方面的已证实疗效,加速了UVC设备在医疗机构中的应用。虽然UVC技术具有若干优势,但仍存在一些缺点。本报告借鉴了与UVC技术在医疗环境中使用相关的研究、指南和实践经验,探讨了UVC设备的疗效、优势和缺点,以及它们在无菌药物配制制药单元中的应用。
选取了相关研究、指南和实践经验。UVC技术具有快速消毒、减少对化学药剂的依赖、废物最少以及不受手动消毒变异性影响等优势,这使其在配制环境中维持无菌条件方面特别有价值。然而,一些缺点仍然存在,因为它是一种依赖微生物的方法,目前尚无确保有效性的标准化方法。
本观点性文章强调了UCV技术在制药配制单元中的有效性,证明它是传统使用的手动和依赖操作人员方法的可行替代方案。然而,需要标准化方法来评估UVC设备。