Eskinder Henok, Zhang Yang
Department of Pathology, Walter Reed National Miliary Medical Center, Bethesda, MD, USA.
Joint Pathology Center, Silver Spring, MD, USA.
Head Neck Pathol. 2025 Feb 25;19(1):24. doi: 10.1007/s12105-025-01765-3.
Tissue eosinophilia is a common finding during histopathologic evaluation and recognizing its presence oftentimes aids pathologists in arriving at the correct diagnosis. The head and neck region is an anatomic location where an abundance of eosinophil-rich disorders occur. In this review, we seek to provide an overview of eosinophil morphology, production, regulation, lifecycle, recruitment, function, and mediators. We will also summarize the most commonly diagnosed eosinophil-rich disorders, both non-neoplastic and neoplastic, occurring in the head and neck.
组织嗜酸性粒细胞增多是组织病理学评估中常见的发现，认识到其存在通常有助于病理学家做出正确诊断。头颈部是一个发生大量富含嗜酸性粒细胞疾病的解剖部位。在本综述中，我们旨在概述嗜酸性粒细胞的形态、产生、调节、生命周期、募集、功能和介质。我们还将总结头颈部最常见的非肿瘤性和肿瘤性富含嗜酸性粒细胞的疾病。
