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GLP-1: The Progenitor Hormone.

作者信息

Buchwald Henry

机构信息

University of Minnesota, Minneapolis, USA.

出版信息

Obes Surg. 2025 Mar;35(3):1195-1196. doi: 10.1007/s11695-025-07757-0.

DOI:10.1007/s11695-025-07757-0
PMID:39998779
Abstract
摘要

相似文献

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GLP-1: The Progenitor Hormone.胰高血糖素样肽-1:原始激素
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2
Insulinotropic hormone glucagon-like peptide-1 differentiation of human pancreatic islet-derived progenitor cells into insulin-producing cells.促胰岛素激素胰高血糖素样肽-1将人胰岛来源的祖细胞分化为胰岛素分泌细胞。
Endocrinology. 2002 Aug;143(8):3152-61. doi: 10.1210/endo.143.8.8973.
3
GLP-1RA therapy increases circulating vascular regenerative cell content in people living with type 2 diabetes.GLP-1RA 治疗可增加 2 型糖尿病患者循环中的血管再生细胞含量。
Am J Physiol Heart Circ Physiol. 2024 Aug 1;327(2):H370-H376. doi: 10.1152/ajpheart.00257.2024. Epub 2024 Jun 14.
4
Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain.新型 GLP-1 拟肽被开发用于治疗 2 型糖尿病,可促进大脑祖细胞增殖。
J Neurosci Res. 2011 Apr;89(4):481-9. doi: 10.1002/jnr.22565. Epub 2011 Jan 10.
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Glucagon-like peptide-1 stimulates luteinizing hormone-releasing hormone secretion in a rodent hypothalamic neuronal cell line.胰高血糖素样肽-1刺激啮齿动物下丘脑神经元细胞系中的促黄体生成素释放激素分泌。
J Clin Invest. 1998 Mar 15;101(6):1334-41. doi: 10.1172/JCI610.
6
Circulating levels of endothelial progenitor cells are associated with better cognitive function in older adults with glucagon-like peptide 1 receptor agonist-treated type 2 diabetes.循环内皮祖细胞水平与接受胰高血糖素样肽 1 受体激动剂治疗的 2 型糖尿病老年患者更好的认知功能相关。
Diabetes Res Clin Pract. 2023 Jun;200:110688. doi: 10.1016/j.diabres.2023.110688. Epub 2023 Apr 26.
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Endothelial Progenitor Cells as Pathogenetic and Diagnostic Factors, and Potential Targets for GLP-1 in Combination with Metabolic Syndrome and Chronic Obstructive Pulmonary Disease.内皮祖细胞作为代谢综合征和慢性阻塞性肺疾病的发病机制和诊断因素,以及 GLP-1 联合治疗的潜在靶点。
Int J Mol Sci. 2019 Mar 4;20(5):1105. doi: 10.3390/ijms20051105.
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Single incretin receptor knockout mice do not compensate by increasing glucose-stimulated secretion of the remaining incretin hormone.单一肠促胰岛素受体敲除小鼠不会通过增加剩余肠促胰岛素激素的葡萄糖刺激分泌来进行代偿。
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Endogenous GLP-1 acts on paraventricular nucleus to suppress feeding: projection from nucleus tractus solitarius and activation of corticotropin-releasing hormone, nesfatin-1 and oxytocin neurons.内源性 GLP-1 通过作用于室旁核来抑制摄食:来自孤束核的投射以及促肾上腺皮质激素释放激素、nesfatin-1 和催产素神经元的激活。
Biochem Biophys Res Commun. 2014 Aug 22;451(2):276-81. doi: 10.1016/j.bbrc.2014.07.116. Epub 2014 Aug 1.
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Degradation of the Incretin Hormone Glucagon-Like Peptide-1 (GLP-1) by Enterococcus faecalis Metalloprotease GelE.肠球菌金属蛋白酶 GelE 降解肠降血糖素激素胰高血糖素样肽-1(GLP-1)。
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本文引用的文献

1
Ockham's razor and the metabolic syndrome.奥卡姆剃刀与代谢综合征
Surg Obes Relat Dis. 2021 Jul;17(7):1236-1243. doi: 10.1016/j.soard.2021.04.004. Epub 2021 Apr 9.
2
The evolution of metabolic/bariatric surgery.代谢/减重手术的发展历程。
Obes Surg. 2014 Aug;24(8):1126-35. doi: 10.1007/s11695-014-1354-3.
3
Ileal effect on blood glucose, HbA1c, and GLP-1 in Goto-Kakizaki rats.回肠对五岛-纪崎大鼠血糖、糖化血红蛋白和胰高血糖素样肽-1的影响。
Obes Surg. 2014 Nov;24(11):1954-60. doi: 10.1007/s11695-014-1307-x.
4
Effects on GLP-1, PYY, and leptin by direct stimulation of terminal ileum and cecum in humans: implications for ileal transposition.直接刺激人体回肠末端和盲肠对胰高血糖素样肽-1、酪酪肽和瘦素的影响:对回肠转位的启示
Surg Obes Relat Dis. 2014 Sep-Oct;10(5):780-6. doi: 10.1016/j.soard.2014.01.032. Epub 2014 Feb 17.
5
Molecular physiology of glucagon-like peptide-1 insulin secretagogue action in pancreatic β cells.胰β细胞中胰高血糖素样肽-1 胰岛素促分泌剂作用的分子生理学
Prog Biophys Mol Biol. 2011 Nov;107(2):236-47. doi: 10.1016/j.pbiomolbio.2011.07.005. Epub 2011 Jul 19.
6
Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis.减肥手术后的体重与2型糖尿病:系统评价与荟萃分析
Am J Med. 2009 Mar;122(3):248-256.e5. doi: 10.1016/j.amjmed.2008.09.041.
7
Who would have thought it? An operation proves to be the most effective therapy for adult-onset diabetes mellitus.谁能想到呢?事实证明,手术是治疗成人型糖尿病最有效的疗法。
Ann Surg. 1995 Sep;222(3):339-50; discussion 350-2. doi: 10.1097/00000658-199509000-00011.