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代谢/减重手术的发展历程。

The evolution of metabolic/bariatric surgery.

机构信息

Department of Surgery, University of Minnesota, 420 Delaware Street SE, MMC 290, Minneapolis, MN, 55455, USA,

出版信息

Obes Surg. 2014 Aug;24(8):1126-35. doi: 10.1007/s11695-014-1354-3.

DOI:10.1007/s11695-014-1354-3
PMID:25008469
Abstract

Metabolic surgery is defined as "the operative manipulation of a normal organ or organ system to achieve a biological result for a potential health gain." The evolution of metabolic/bariatric surgery can be viewed from several perspectives: (1) realization that bariatric surgery has always been and will always be metabolic surgery; (2) lessons to be learned from the six dominant procedures; (3) overview of the other operations that have been proposed; (4) discussion of mechanisms of action; (5) physiology of energy metabolism; and (6) introduction to the emerging concept of inflammation. This review will end with thoughts on the present and future outcomes from the knowledge we have gained from metabolic/bariatric surgery. The author concludes with the statement: Metabolic surgery is cognitive surgery.

摘要

代谢手术被定义为“对正常器官或器官系统进行手术操作,以获得潜在健康收益的生物学结果”。代谢/减重手术的发展可以从几个角度来看待:(1)认识到减重手术一直是并且将永远是代谢手术;(2)从六种主要手术中吸取的经验教训;(3)对已提出的其他手术的概述;(4)对作用机制的讨论;(5)能量代谢生理学;(6)炎症这一新兴概念的引入。本综述将从我们从代谢/减重手术中获得的知识来讨论当前和未来的结果,并以此结束。作者最后指出:代谢手术是认知手术。

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Effects on GLP-1, PYY, and leptin by direct stimulation of terminal ileum and cecum in humans: implications for ileal transposition.直接刺激人体回肠末端和盲肠对胰高血糖素样肽-1、酪酪肽和瘦素的影响:对回肠转位的启示
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GLP-1: The Progenitor Hormone.胰高血糖素样肽-1:原始激素
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When Should the Treatment of Obesity in Thyroid Disease Begin?甲状腺疾病中的肥胖治疗应何时开始?
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