Mori H, Sugie S, Hirono I, Yamada K, Niwa H, Ojika M
Mutat Res. 1985 May-Jun;143(1-2):75-8. doi: 10.1016/0165-7992(85)90108-3.
The genotoxicity of ptaquiloside (PT), recently isolated from bracken fern and shown to be carcinogenic, was examined by means of the hepatocyte primary culture/DNA-repair test. PT elicited clear unscheduled DNA synthesis with a dose-response effect. The result indicates that PT is a genotoxic carcinogen.
从蕨菜中最近分离出的ptaquiloside（PT）具有致癌性，利用肝细胞原代培养/DNA修复试验对其遗传毒性进行了检测。PT引发了明显的程序外DNA合成，呈现剂量反应效应。结果表明PT是一种遗传毒性致癌物。
