Fouad Shereen, Usman Muhammad, Kabir Ra'eesa, Rajasekaran Arvind, Morlese John, Nagori Pankaj, Bhatia Bahadar
School of Computer Science and Digital Technologies, Aston University, Birmingham, UK.
Sandwell and West Birmingham Hospitals NHS Trust, West Birmingham, UK.
J Imaging Inform Med. 2025 Feb 26. doi: 10.1007/s10278-025-01444-3.
In March 2020, the British Society of Thoracic Imaging (BSTI) introduced a reporting guidance for COVID-19 detection to streamline standardised reporting and enhance agreement between radiologists. However, most current DL methods do not conform to this guidance. This study introduces a multi-class deep learning (DL) model to identify BSTI COVID-19 categories within CT volumes, classified as 'Classic', 'Probable', 'Indeterminate', or 'Non-COVID'. A total of 56 CT pseudoanonymised images were collected from patients with suspected COVID-19 and annotated by an experienced chest subspecialty radiologist following the BSTI guidance. We evaluated the performance of multiple DL-based models, including three-dimensional (3D) ResNet architectures, pre-trained on the Kinetics-700 video dataset. For better interpretability of the results, our approach incorporates a post-hoc visual explainability feature to highlight the areas of the image most indicative of the COVID-19 category. Our four-class classification DL framework achieves an overall accuracy of 75%. However, the model struggled to detect the 'Indeterminate' COVID-19 group, whose removal significantly improved the model's accuracy to 90%. The proposed explainable multi-classification DL model yields accurate detection of 'Classic', 'Probable', and 'Non-COVID' categories with poor detection ability for 'Indeterminate' COVID-19 cases. These findings are consistent with clinical studies that aimed at validating the BSTI reporting manually amongst consultant radiologists.
2020年3月,英国胸科影像学会(BSTI)出台了一项关于新冠病毒(COVID-19)检测的报告指南,以简化标准化报告流程,并提高放射科医生之间的一致性。然而,目前大多数深度学习(DL)方法并不符合该指南。本研究引入了一种多分类深度学习模型,用于在CT容积中识别BSTI新冠病毒类别,分为“典型”“可能”“不确定”或“非新冠”。我们从疑似感染新冠病毒的患者中收集了56张CT伪匿名图像,并由一位经验丰富的胸部专科放射科医生按照BSTI指南进行标注。我们评估了多个基于深度学习的模型的性能,包括在Kinetics-700视频数据集上预训练的三维(3D)ResNet架构。为了更好地解释结果,我们的方法纳入了事后视觉可解释性特征,以突出图像中最能表明新冠病毒类别的区域。我们的四分类深度学习框架总体准确率达到75%。然而,该模型难以检测出“不确定”的新冠病毒组,去除该组后模型准确率显著提高至90%。所提出的可解释多分类深度学习模型能够准确检测出“典型”“可能”和“非新冠”类别,但对“不确定”的新冠病毒病例检测能力较差。这些发现与旨在在放射科会诊医生中手动验证BSTI报告的临床研究结果一致。