McDonald H R, Schatz H
Retina. 1985 Winter-Spring;5(1):5-10. doi: 10.1097/00006982-198500510-00002.
The authors reviewed the preoperative, postoperative, and follow-up examinations, fundus photographs, and fluorescein angiograms of 175 eyes with proliferative diabetic retinopathy treated with panretinal photocoagulation. Seventy-five (43%) of the treated eyes developed increased macular edema 6-10 weeks following laser treatment. Follow-ups ranged from 3 months to 48 months, with a median follow-up of 15 months. Fluorescein angiography revealed that the postlaser increase in macular edema persisted in 47 of the 175 eyes (27%). Fourteen eyes (8%) treated with laser developed chronic macular edema and visual loss of two or more lines. Inflammation and altered retinal blood flow are possible pathogenetic mechanisms responsible for the development of postpanretinal photocoagulation macular edema.
作者回顾了175例接受全视网膜光凝治疗的增殖性糖尿病视网膜病变患者术前、术后及随访检查、眼底照片和荧光素血管造影。75只（43%）接受治疗的眼睛在激光治疗后6 - 10周出现黄斑水肿加重。随访时间为3个月至48个月，中位随访时间为15个月。荧光素血管造影显示，175只眼中有47只（27%）在激光治疗后黄斑水肿持续存在。14只（8%）接受激光治疗的眼睛出现慢性黄斑水肿且视力下降两行或更多。炎症和视网膜血流改变可能是全视网膜光凝后黄斑水肿发生的致病机制。
