Manalu Lamhot Parulian, Adinegoro Himawan, Yustiningsih Nenie, Luthfiyanti Rohmah, Purwanto Wahyu, Pongtuluran Olivia Bunga, Atmaji Priyo, Hidayat Taufik, Henanto Henky, Asgar Ali, Nasori Achmad Sofian, Triyono Agus, Elya Berna, Arif Abdullah Bin
Research Center for Agroindustry, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Tangerang, Indonesia.
Research Center for Appropriate Technology, Research Organization for Agriculture and Food, National Research and Innovation Agency (BRIN), Tangerang, Indonesia.
Scientifica (Cairo). 2025 Feb 20;2025:7146758. doi: 10.1155/sci5/7146758. eCollection 2025.
species have been used as herbal medicines in traditional Asian medicine. One of the species that has the potential as a medicinal plant and is still limited in its studies is . This study investigated the effects of drying methods, namely, freeze drying (FD) and hot air drying (HAD), on bioactive compounds, phenolics, flavonoids, and antioxidants in leaves and stems. The content of bioactive compounds in . leaves and stems was identified with gas chromatography-mass spectrometry (GC-MS) analysis. In addition, the antioxidant activity of was also measured. The results of GC-MS on contain major bioactive compounds including gamma.-Sitosterol, Glutinol, Friedelan-3-one, Squalene, Ergost-5-en-3-ol, (3.β.)-, Erythritol, and Neophytadiene. The main component identified in the leaf and stem extracts of is gamma-sitosterol (± 15%), which shows anticancer and antidiabetic effects. The antioxidant activity in with the FD method was higher than that with the HAD method. This study suggests that FD was considered appropriate and should be used to maintain the content of important bioactive compounds and antioxidant activity in . These findings suggest that further research and development of bioactive compounds essential for their pharmacological properties in may be warranted, with the potential for developing new drugs.
一些物种在传统亚洲医学中被用作草药。作为一种有潜力的药用植物但研究仍有限的物种之一是[物种名称未给出]。本研究调查了干燥方法，即冷冻干燥（FD）和热风干燥（HAD），对[物种名称未给出]叶片和茎中生物活性化合物、酚类、黄酮类和抗氧化剂的影响。通过气相色谱 - 质谱联用（GC - MS）分析确定了[物种名称未给出]叶片和茎中生物活性化合物的含量。此外，还测定了[物种名称未给出]的抗氧化活性。GC - MS对[物种名称未给出]的分析结果显示主要生物活性化合物包括γ - 谷甾醇、羽扇豆醇、木栓酮、角鲨烯、麦角甾 - 5 - 烯 - 3 - 醇、（3.β.） - 、赤藓醇和新植二烯。在[物种名称未给出]的叶和茎提取物中鉴定出的主要成分是γ - 谷甾醇（±15%），其具有抗癌和抗糖尿病作用。采用FD方法时[物种名称未给出]的抗氧化活性高于采用HAD方法时的。本研究表明，FD被认为是合适的，应被用于维持[物种名称未给出]中重要生物活性化合物的含量和抗氧化活性。这些发现表明，可能有必要对[物种名称未给出]中对其药理特性至关重要的生物活性化合物进行进一步的研究和开发，具有开发新药的潜力。
