Thamer Faten Hameed, Thamer Noah
Department of Chemistry, Sana'a University, Sana'a, Yemen.
Heliyon. 2023 Jun 3;9(6):e16861. doi: 10.1016/j.heliyon.2023.e16861. eCollection 2023 Jun.
(L.) (, commonly known as Handal in Yemen and other Arabic countries, is a plant with a wide range of pharmacological properties. These properties are attributed to secondary metabolites, known as phytochemicals, present in the plant. In this study, the seed of were extracted using dichloromethane, and the resulting oil extract was screened to identify active phytoconstituents using gas chromatography - Mass spectrometry (GC-MS). The gas chromatography - Mass spectrometry is used to identification of the phytoconstituents and the spectrum of unknown compounds were compared with the compounds stored in the National Institute of Standards and Technology Mass Spectral database (NIST) and WILEY library of GC-MS. A total of fifty five compounds appeared in GC-MS chromatogram, twenty-four major bioactive compounds were identified in the present study. The major components of the oil extract were found to be carotenes, phenols, esters, and steroids. From the GC-MS chromatogram of dichloromethane seeds oil extract, some of the identified components possess pharmacological actions as per information available in the literature. One of the major component identified in the seed oil extract was isooctylphthalate (58%), which exhibit strong antimicrobials effect. Therefore, is considered to be a natural source of isooctylphthalate. From the results, this study is the first to report the presence of various bioactive components of phytopharmaceutical importance in .
（L.）（在也门和其他阿拉伯国家通常被称为汉达尔）是一种具有广泛药理特性的植物。这些特性归因于该植物中存在的次生代谢产物，即植物化学物质。在本研究中，使用二氯甲烷提取了（植物名称缺失）的种子，并对所得油提取物进行了筛选，以使用气相色谱 - 质谱联用仪（GC-MS）鉴定活性植物成分。气相色谱 - 质谱联用仪用于鉴定植物成分，并将未知化合物的光谱与存储在美国国家标准与技术研究院质谱数据库（NIST）和GC-MS的WILEY库中的化合物进行比较。共有五十五种化合物出现在GC-MS色谱图中，本研究鉴定出了二十四种主要生物活性化合物。油提取物的主要成分被发现是胡萝卜素、酚类、酯类和类固醇。根据文献中可用的信息，从二氯甲烷种子油提取物的GC-MS色谱图来看，一些鉴定出的成分具有药理作用。在（植物名称缺失）种子油提取物中鉴定出的主要成分之一是邻苯二甲酸异辛酯（58%），它具有很强的抗菌作用。因此，（植物名称缺失）被认为是邻苯二甲酸异辛酯的天然来源。从结果来看，本研究首次报道了（植物名称缺失）中存在具有植物药学重要性的各种生物活性成分。
