Sahin Enes, Sahin Kazim, Ulutas Mehmet Esref, Turan Yakup, Güler Sertac Ata, Simsek Turgay, Cantürk Nuh Zafer
Department of General Surgery, Kocaeli University Faculty of Medicine, Kocaeli, TUR.
Department of General Surgery, Kandıra State Hospital, Kocaeli, TUR.
Cureus. 2025 Jan 27;17(1):e78097. doi: 10.7759/cureus.78097. eCollection 2025 Jan.
Introduction It is estimated that the world population is getting older. Accordingly, the incidence of GI tract malignancies is increasing in patients over 65 years of age. This study aims to investigate the impact of frailty on the postoperative course of elderly patients with gastrointestinal malignancies (GIM). Methodology This study recruited 120 elderly patients who had been operated on for GIM. Variables such as age, readmission rate, duration of hospitalization, and frailty index (FI) criteria (fatigue, endurance, walking/running speed, comorbidities, and weight loss) were determined, and the FI was calculated. The relationship between the FI and postoperative complications in the study participants was then evaluated. Results The study involved 120 patients with gastric, colon, and rectal cancers. The mean age of the participants was 72.79 ± 5.4 years, of which 56.6% (68) were male and 43.3% (52) were female. The average hospitalization duration was 6.7 days, and the average ICU stay duration was 2.2 days. There was a correlation between the age of the patients and their FI scores (FIS). Conclusion It was determined that the FIS increases in parallel with increasing age among the elderly. Furthermore, the presence of preoperative comorbidities with old age increases postoperative mortality and morbidity.
引言 据估计,世界人口正在老龄化。因此,65岁以上患者胃肠道恶性肿瘤的发病率正在上升。本研究旨在调查虚弱对老年胃肠道恶性肿瘤(GIM)患者术后病程的影响。
方法 本研究招募了120例接受GIM手术的老年患者。确定了年龄、再入院率、住院时间和虚弱指数(FI)标准(疲劳、耐力、步行/跑步速度、合并症和体重减轻)等变量,并计算了FI。然后评估研究参与者中FI与术后并发症之间的关系。
结果 该研究涉及120例胃癌、结肠癌和直肠癌患者。参与者的平均年龄为72.79±5.4岁,其中56.6%(68例)为男性,43.3%(52例)为女性。平均住院时间为6.7天,平均重症监护病房停留时间为2.2天。患者年龄与其FI评分(FIS)之间存在相关性。
结论 确定老年人中FIS随年龄增长而平行增加。此外,老年患者术前合并症的存在会增加术后死亡率和发病率。