Section of Gastrointestinal, Tumor and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
J Am Geriatr Soc. 2013 Sep;61(9):1608-14. doi: 10.1111/jgs.12401. Epub 2013 Aug 8.
To determine whether 30-day postoperative mortality, complications, failure-to-rescue (FTR) rates, and postoperative length of stay increase with advancing age.
Retrospective cohort study.
Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program.
Individuals undergoing nonemergent major general surgeries between 2005 and 2008 were studied (N = 165,600).
Postoperative outcomes of interest were complications occurring within 30 days of the index operation, return to the operating room within 30 days, FTR after a postoperative complication, postsurgical length of stay, and 30-day mortality.
Postoperative mortality, overall morbidity, and each type of postoperative complication increased with increasing age. Rates of FTR after each type of postoperative complication also increased with age. Mortality in individuals aged 80 and older after renal insufficiency (43.3%), stroke (36.5%), myocardial infarction (MI) (35.6%), and pulmonary complications (25-39%) were particularly high. Median postoperative length of stay increased with age after surgical site infection, urinary tract infection, pneumonia, return to the operating room, and overall morbidity but not after venous thromboembolism, stroke, MI, renal insufficiency, failure to wean from the ventilator, or reintubation.
Thirty-day mortality and complication and FTR rates increase with age after nonemergent general surgeries. Individuals aged 80 and older have especially high mortality after renal, cardiovascular, and pulmonary complications. Surgeons need to be more selective with advancing age regarding who will benefit from the surgical intervention.
确定术后 30 天死亡率、并发症、救治失败率(FTR)以及术后住院时间是否随年龄增长而增加。
回顾性队列研究。
参与美国外科医师学会国家外科质量改进计划的医院。
2005 年至 2008 年间接受非紧急大普通外科手术的个体(n=165600)。
感兴趣的术后结果包括指数手术后 30 天内发生的并发症、30 天内返回手术室、术后并发症后的 FTR、术后住院时间和 30 天死亡率。
术后死亡率、总发病率和每种术后并发症的发生率随年龄增长而增加。每种术后并发症后的 FTR 发生率也随年龄增长而增加。80 岁及以上患者因肾功能不全(43.3%)、中风(36.5%)、心肌梗死(MI)(35.6%)和肺部并发症(25-39%)而导致的死亡率特别高。在手术部位感染、尿路感染、肺炎、返回手术室和总发病率后,年龄与术后住院时间中位数呈正相关,但静脉血栓栓塞、中风、MI、肾功能不全、呼吸机脱机失败或重新插管后则不然。
非紧急普通手术后,30 天死亡率、并发症和 FTR 率随年龄增长而增加。80 岁及以上患者因肾、心血管和肺部并发症而导致的死亡率特别高。对于年龄增长的患者,外科医生在选择是否进行手术干预时需要更加慎重,以确定谁将从中受益。