• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

非紧急普通外科手术后年龄增长与 30 天不良结局。

Advancing age and 30-day adverse outcomes after nonemergent general surgeries.

机构信息

Section of Gastrointestinal, Tumor and Endocrine Surgery, Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado.

出版信息

J Am Geriatr Soc. 2013 Sep;61(9):1608-14. doi: 10.1111/jgs.12401. Epub 2013 Aug 8.

DOI:10.1111/jgs.12401
PMID:23927841
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4119758/
Abstract

OBJECTIVES

To determine whether 30-day postoperative mortality, complications, failure-to-rescue (FTR) rates, and postoperative length of stay increase with advancing age.

DESIGN

Retrospective cohort study.

SETTING

Hospitals participating in the American College of Surgeons National Surgical Quality Improvement Program.

PARTICIPANTS

Individuals undergoing nonemergent major general surgeries between 2005 and 2008 were studied (N = 165,600).

MEASUREMENTS

Postoperative outcomes of interest were complications occurring within 30 days of the index operation, return to the operating room within 30 days, FTR after a postoperative complication, postsurgical length of stay, and 30-day mortality.

RESULTS

Postoperative mortality, overall morbidity, and each type of postoperative complication increased with increasing age. Rates of FTR after each type of postoperative complication also increased with age. Mortality in individuals aged 80 and older after renal insufficiency (43.3%), stroke (36.5%), myocardial infarction (MI) (35.6%), and pulmonary complications (25-39%) were particularly high. Median postoperative length of stay increased with age after surgical site infection, urinary tract infection, pneumonia, return to the operating room, and overall morbidity but not after venous thromboembolism, stroke, MI, renal insufficiency, failure to wean from the ventilator, or reintubation.

CONCLUSION

Thirty-day mortality and complication and FTR rates increase with age after nonemergent general surgeries. Individuals aged 80 and older have especially high mortality after renal, cardiovascular, and pulmonary complications. Surgeons need to be more selective with advancing age regarding who will benefit from the surgical intervention.

摘要

目的

确定术后 30 天死亡率、并发症、救治失败率(FTR)以及术后住院时间是否随年龄增长而增加。

设计

回顾性队列研究。

地点

参与美国外科医师学会国家外科质量改进计划的医院。

参与者

2005 年至 2008 年间接受非紧急大普通外科手术的个体(n=165600)。

测量

感兴趣的术后结果包括指数手术后 30 天内发生的并发症、30 天内返回手术室、术后并发症后的 FTR、术后住院时间和 30 天死亡率。

结果

术后死亡率、总发病率和每种术后并发症的发生率随年龄增长而增加。每种术后并发症后的 FTR 发生率也随年龄增长而增加。80 岁及以上患者因肾功能不全(43.3%)、中风(36.5%)、心肌梗死(MI)(35.6%)和肺部并发症(25-39%)而导致的死亡率特别高。在手术部位感染、尿路感染、肺炎、返回手术室和总发病率后,年龄与术后住院时间中位数呈正相关,但静脉血栓栓塞、中风、MI、肾功能不全、呼吸机脱机失败或重新插管后则不然。

结论

非紧急普通手术后,30 天死亡率、并发症和 FTR 率随年龄增长而增加。80 岁及以上患者因肾、心血管和肺部并发症而导致的死亡率特别高。对于年龄增长的患者,外科医生在选择是否进行手术干预时需要更加慎重,以确定谁将从中受益。

相似文献

1
Advancing age and 30-day adverse outcomes after nonemergent general surgeries.非紧急普通外科手术后年龄增长与 30 天不良结局。
J Am Geriatr Soc. 2013 Sep;61(9):1608-14. doi: 10.1111/jgs.12401. Epub 2013 Aug 8.
2
Risk of major nonemergent inpatient general surgical procedures in patients on long-term dialysis.长期血液透析患者接受大型非紧急住院普外科手术的风险。
JAMA Surg. 2013 Feb;148(2):137-43. doi: 10.1001/2013.jamasurg.347.
3
The significance of preoperative impaired sensorium on surgical outcomes in nonemergent general surgical operations.术前意识障碍对非紧急普通外科手术手术结果的意义。
JAMA Surg. 2015 Jan;150(1):30-6. doi: 10.1001/jamasurg.2014.863.
4
Complications and Failure to Rescue After Inpatient Noncardiac Surgery in the Veterans Affairs Health System.退伍军人事务部医疗体系中住院非心脏手术后的并发症和抢救失败。
JAMA Surg. 2016 Dec 1;151(12):1157-1165. doi: 10.1001/jamasurg.2016.2920.
5
Association of Frailty With Failure to Rescue After Low-Risk and High-Risk Inpatient Surgery.虚弱与低风险和高风险住院手术失败后救援失败的关联。
JAMA Surg. 2018 May 16;153(5):e180214. doi: 10.1001/jamasurg.2018.0214.
6
A Tool to Estimate Risk of 30-day Mortality and Complications After Hip Fracture Surgery: Accurate Enough for Some but Not All Purposes? A Study From the ACS-NSQIP Database.一种用于评估髋部骨折手术后 30 天死亡率和并发症风险的工具:对于某些目的足够准确,但并非所有目的都准确?来自 ACS-NSQIP 数据库的研究。
Clin Orthop Relat Res. 2022 Dec 1;480(12):2335-2346. doi: 10.1097/CORR.0000000000002294. Epub 2022 Jun 27.
7
Impact of specific postoperative complications on the outcomes of emergency general surgery patients.特定术后并发症对急诊普通外科患者结局的影响。
J Trauma Acute Care Surg. 2015 May;78(5):912-8; discussion 918-9. doi: 10.1097/TA.0000000000000611.
8
Development and Validation of a Prediction Model for Stroke, Cardiac, and Mortality Risk After Non-Cardiac Surgery.非心脏手术后卒中、心脏和死亡风险预测模型的开发和验证。
J Am Heart Assoc. 2021 Feb 16;10(4):e018013. doi: 10.1161/JAHA.120.018013. Epub 2021 Jan 30.
9
Hospital variation in mortality after emergent bowel resections: The role of failure-to-rescue.急症肠切除术后死亡率的医院差异:未抢救成功的作用。
J Trauma Acute Care Surg. 2018 May;84(5):702-710. doi: 10.1097/TA.0000000000001827.
10
Patient factors associated with 30-day morbidity, mortality, and length of stay after surgery for subdural hematoma: a study of the American College of Surgeons National Surgical Quality Improvement Program.与硬膜下血肿手术后30天发病率、死亡率及住院时间相关的患者因素:美国外科医师学会国家外科质量改进计划的一项研究
J Neurosurg. 2016 Mar;124(3):760-6. doi: 10.3171/2015.2.JNS142721. Epub 2015 Aug 28.

引用本文的文献

1
Gigantomastia: Advancing a Preference Score System to Enhance Care Quality and Life Standards.巨乳症:推进偏好评分系统以提高护理质量和生活水平。
Aesthetic Plast Surg. 2025 Aug;49(15):4256-4264. doi: 10.1007/s00266-025-04831-x. Epub 2025 Apr 3.
2
Major Adverse Cardiovascular Events After Colorectal Cancer Surgery, Oncological Outcomes, and Long-term Mortality: A Nationwide Retrospective Propensity Score-Matched Cohort Study.结直肠癌手术后的主要不良心血管事件、肿瘤学结局和长期死亡率:一项全国性回顾性倾向评分匹配队列研究
Ann Surg Open. 2025 Mar 6;6(1):e560. doi: 10.1097/AS9.0000000000000560. eCollection 2025 Mar.
3
Calculation of the Frailty Index and Precautions for Elderly Patients Undergoing Gastrointestinal Cancer Surgery.老年胃肠癌手术患者衰弱指数的计算及注意事项
Cureus. 2025 Jan 27;17(1):e78097. doi: 10.7759/cureus.78097. eCollection 2025 Jan.
4
Improving the palliative-procedure decision-making process for patients with peritoneal carcinomatosis: A secondary analysis.提高腹膜癌病患者姑息治疗决策过程的质量:二次分析。
Gynecol Oncol. 2024 Sep;188:125-130. doi: 10.1016/j.ygyno.2024.06.014. Epub 2024 Jul 1.
5
Elective Surgery Trends and Outcomes of Nonagenarians and Centenarians in Otolaryngology-Head and Neck Surgery: A NSQIP Study.耳鼻喉头颈外科 90 岁及以上和百岁老人择期手术趋势及结局的 NSQIP 研究
Laryngoscope. 2024 Sep;134(9):3989-3996. doi: 10.1002/lary.31446. Epub 2024 Apr 8.
6
Clin-STAR corner: Practice-changing advances at the interface of surgery and geriatrics.临床之星专栏:外科与老年医学交界处的改变实践的进展。
J Am Geriatr Soc. 2024 Jul;72(7):1959-1963. doi: 10.1111/jgs.18783. Epub 2024 Jan 27.
7
Is there an outcome benefit? Patient engagement technology in addition to the electronic medical record patient portal following elective colorectal surgery.是否存在结局获益?择期结直肠手术后,除电子病历患者门户之外的患者参与技术。
Surg Endosc. 2023 Dec;37(12):9275-9282. doi: 10.1007/s00464-023-10478-z. Epub 2023 Oct 25.
8
Geriatric Surgery Produces a Hypoactive Molecular Phenotype in the Monocyte Immune Gene Transcriptome.老年外科手术在单核细胞免疫基因转录组中产生低活性分子表型。
J Clin Med. 2023 Sep 28;12(19):6271. doi: 10.3390/jcm12196271.
9
A Real-Time Neurophysiologic Stress Test for the Aging Brain: Novel Perioperative and ICU Applications of EEG in Older Surgical Patients.实时神经生理应激测试在老年大脑中的应用:老年手术患者 EEG 在围手术期和 ICU 的新应用。
Neurotherapeutics. 2023 Jul;20(4):975-1000. doi: 10.1007/s13311-023-01401-4. Epub 2023 Jul 12.
10
Comparison of long-term quality of life outcomes between endoscopic vacuum therapy and other treatments for upper gastrointestinal leaks.内镜下真空治疗与其他治疗方法治疗上消化道漏的长期生活质量结局比较。
Surg Endosc. 2023 Aug;37(8):6538-6547. doi: 10.1007/s00464-023-10181-z. Epub 2023 Jun 12.

本文引用的文献

1
Preoperative cognitive dysfunction is related to adverse postoperative outcomes in the elderly.术前认知功能障碍与老年人术后不良结局有关。
J Am Coll Surg. 2012 Jul;215(1):12-7; discussion 17-8. doi: 10.1016/j.jamcollsurg.2012.02.007. Epub 2012 May 22.
2
Major abdominal surgery in nursing home residents: a national study.养老院居民的大型腹部手术:一项全国性研究。
Ann Surg. 2011 Dec;254(6):921-6. doi: 10.1097/SLA.0b013e3182383a78.
3
Frailty predicts increased hospital and six-month healthcare cost following colorectal surgery in older adults.虚弱预测老年人结直肠手术后住院和六个月医疗保健费用增加。
Am J Surg. 2011 Nov;202(5):511-4. doi: 10.1016/j.amjsurg.2011.06.017. Epub 2011 Sep 3.
4
Operative outcomes beyond 30-day mortality: colorectal cancer surgery in oldest old.30 天死亡率以外的手术结果:最年长老年人的结直肠癌手术。
Ann Surg. 2011 May;253(5):947-52. doi: 10.1097/SLA.0b013e318216f56e.
5
Thirty-day postoperative mortality after colorectal cancer surgery in England.英格兰结直肠癌手术后 30 天的术后死亡率。
Gut. 2011 Jun;60(6):806-13. doi: 10.1136/gut.2010.232181. Epub 2011 Apr 12.
6
Impact of advancing age on abdominal surgical outcomes.年龄增长对腹部手术结局的影响。
Arch Surg. 2009 Dec;144(12):1108-14. doi: 10.1001/archsurg.2009.204.
7
Major cancer surgery in the elderly: results from the American College of Surgeons National Surgical Quality Improvement Program.老年人的主要癌症手术:美国外科医师学院国家手术质量改进计划的结果。
Ann Surg. 2010 Feb;251(2):311-8. doi: 10.1097/SLA.0b013e3181b6b04c.
8
Redefining geriatric preoperative assessment using frailty, disability and co-morbidity.利用衰弱、残疾和共病重新定义老年患者术前评估。
Ann Surg. 2009 Sep;250(3):449-55. doi: 10.1097/SLA.0b013e3181b45598.
9
The significance of discharge to skilled care after abdominopelvic surgery in older adults.老年患者腹盆腔手术后转至专业护理机构的意义。
Ann Surg. 2009 Feb;249(2):250-5. doi: 10.1097/SLA.0b013e318195e12f.
10
The effect of age on short-term outcomes after pancreatic resection: a population-based study.年龄对胰腺切除术后短期结局的影响:一项基于人群的研究。
Ann Surg. 2008 Sep;248(3):459-67. doi: 10.1097/SLA.0b013e318185e1b3.