Peeling Rosanna W, Fongwen Noah T, Guzman Maria G, Méndez-Rico Jairo Andres, Avumegah Michael Selorm, Jaenisch Thomas, Lackritz Eve M
London School of Hygiene & Tropical Medicine, London, UK.
London School of Hygiene & Tropical Medicine, London, UK; Africa Centres for Disease Control and Prevention, Addis Ababa, Ethiopia.
Lancet Microbe. 2025 Jun;6(6):101057. doi: 10.1016/j.lanmic.2024.101057. Epub 2025 Feb 27.
For diseases with epidemic potential, specimen and data sharing is crucial for sustained research and development of medical countermeasures such as diagnostics, therapeutics, and vaccines. In the case of Zika virus, although a global framework for specimen and data sharing to advance research and development is highly desirable, challenges related to legal, ethical, and intellectual property issues persist. Since the 2015-16 Zika virus outbreak, regional laboratory networks and research partnerships have made some progress in specimen and data sharing among some Zika virus-endemic countries. Pragmatic steps such as securing funds for augmenting laboratory capacity, building biobanks within public health laboratory infrastructures in low-income and middle-income countries, clearly defining the specimens and data that need to be collected, developing standardised protocols, harmonising data system interoperability to facilitate sharing, and defining mechanisms for benefit sharing will pave the way for timely development and deployment of medical countermeasures in public health emergencies.
对于具有流行潜力的疾病,样本和数据共享对于诊断、治疗和疫苗等医学应对措施的持续研发至关重要。以寨卡病毒为例,尽管非常需要一个促进研发的样本和数据共享全球框架,但法律、伦理和知识产权问题带来的挑战依然存在。自2015 - 2016年寨卡病毒疫情爆发以来,区域实验室网络和研究伙伴关系在一些寨卡病毒流行国家之间的样本和数据共享方面取得了一些进展。采取务实措施,如为增强实验室能力筹集资金、在低收入和中等收入国家的公共卫生实验室基础设施内建立生物样本库、明确界定需要收集的样本和数据、制定标准化方案、协调数据系统的互操作性以促进共享以及确定利益共享机制,将为在突发公共卫生事件中及时研发和部署医学应对措施铺平道路。