Rasoulian Pegah, Khadembashiri Mohammad Amin, Amlashi Manoochehr Amin, Ghazanfari Sara, Arbatan Mahsa Noohi, Rabiei Zahra, Danandeh Khashayar, Faridpour Amirabbas, Dehghani Elaheh
Sports medicine research center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.
Neuromusculoskeletal Research Center, Iran University of Medical Sciences, Tehran, Iran.
J Prev Med Hyg. 2025 Jan 31;65(4):E524-E531. doi: 10.15167/2421-4248/jpmh2024.65.4.3271. eCollection 2024 Dec.
Iodine is necessary for the synthesis of thyroid hormones which rely on sufficient levels of iodine. Iodine deficiency (ID) gives rise to various diseases. This is the first study presenting the epidemiology of ID in the Iranian population from 1992 to 2019.
This study was performed based on the analysis of global burden of disease (GBD) study data. Epidemiological indices including prevalence, incidence, and age-standardized disability-adjusted life years (DALYs) were compared in all provinces located in Iran between 1992 and 2019.
The studies' collective conclusions showed that Iran's age-standardized DALYs rate (ASDR) for iodine deficiency dropped from 14.76 to 5.92. Additionally, the ASDR for Iodine Deficiency is clearly trending lower for all provinces. The ASDR for iodine deficiency peaked in 1990 in middle-aged people of both sexes. But later in the year, the pattern changed, with males and older age groups in particular reporting a larger ASDR of iodine deficiency.
The findings of this study show that the burden of iodine deficiency disorder has decreased in different provinces, all age and, males, but some provinces and groups still need more regulations to reduce the burden of iodine deficiency.
碘是合成甲状腺激素所必需的，而甲状腺激素的合成依赖于充足的碘水平。碘缺乏会引发各种疾病。这是第一项呈现1992年至2019年伊朗人群碘缺乏流行病学情况的研究。
本研究基于对全球疾病负担（GBD）研究数据的分析进行。对1992年至2019年伊朗所有省份的流行病学指标进行了比较，包括患病率、发病率和年龄标准化残疾调整生命年（DALY）。
研究的总体结论显示，伊朗碘缺乏的年龄标准化DALY率（ASDR）从14.76降至5.92。此外，所有省份碘缺乏的ASDR明显呈下降趋势。碘缺乏的ASDR在1990年达到峰值，出现在中年男女群体中。但在随后几年，情况发生了变化，尤其是男性和老年群体的碘缺乏ASDR更高。
本研究结果表明，不同省份、所有年龄段以及男性群体的碘缺乏疾病负担均有所下降，但一些省份和群体仍需要更多的管控措施来减轻碘缺乏负担。
