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碘与碘缺乏:一个重新出现的问题的全面综述。

Iodine and Iodine Deficiency: A Comprehensive Review of a Re-Emerging Issue.

机构信息

Military Nutrition Division, U.S. Army Research Institute of Environmental Medicine, 10 General Greene Ave, Natick, MA 01760, USA.

出版信息

Nutrients. 2022 Aug 24;14(17):3474. doi: 10.3390/nu14173474.

DOI:10.3390/nu14173474
PMID:36079737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9459956/
Abstract

Iodine is a mineral nutrient essential for the regulation of a variety of key physiological functions including metabolism and brain development and function in children and adults. As such, iodine intake and status within populations is an area of concern and research focus. This paper will review recently published studies that focus on the re-emerging issue of iodine deficiency as a global concern and declining intake among populations in developed countries. Historically, the implementation of salt-iodization programs worldwide has reduced the incidence of iodine deficiency, but 30% of the world's population is still at risk. Iodine nutrition is a growing issue within industrialized countries including the U.S. as a result of declining iodine intake, in part due to changing dietary patterns and food manufacturing practices. Few countries mandate universal salt iodization policies, and differing agriculture and industry practices and regulations among countries have resulted in inconsistencies in supplementation practices. In the U.S., in spite of salt-iodization policies, mild-to-moderate iodine deficiency is common and appears to be increasing. European countries with the highest incidence of deficiency lack iodization programs. Monitoring the iodine status of at-risk populations and, when appropriate, public health initiatives, appear to be warranted.

摘要

碘是一种矿物质营养素,对调节多种关键生理功能至关重要,包括代谢以及儿童和成人的大脑发育和功能。因此,人群的碘摄入量和状况是一个令人关注和研究的重点领域。本文将综述最近发表的研究,重点关注碘缺乏这一在全球范围内重新出现的问题,以及发达国家人群的摄入量下降问题。从历史上看,全球范围内实施的食盐碘化项目已经降低了碘缺乏症的发病率,但仍有 30%的世界人口面临风险。由于碘摄入量下降,碘营养在包括美国在内的工业化国家日益成为一个问题,部分原因是饮食模式和食品制造做法发生了变化。很少有国家强制实行全民食盐碘化政策,各国之间的农业和工业做法和法规存在差异,导致补充做法不一致。在美国,尽管实施了食盐碘化政策,但仍普遍存在轻度至中度碘缺乏症,而且似乎还在增加。碘缺乏症发病率最高的欧洲国家缺乏碘化项目。似乎有必要对高危人群的碘状况进行监测,并在适当情况下采取公共卫生措施。

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本文引用的文献

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Iodine in Foods and Dietary Supplements: A Collaborative Database Developed by NIH, FDA and USDA.食品和膳食补充剂中的碘:由美国国立卫生研究院、美国食品药品监督管理局和美国农业部共同开发的数据库
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Low Urinary Iodine Concentration Is Associated with Increased Risk for Elevated Plasma Glucose in Females: An Analysis of NHANES 2011-12.尿碘浓度低与女性血浆葡萄糖升高风险增加相关:NHANES 2011-2012 分析。
Nutrients. 2021 Dec 17;13(12):4523. doi: 10.3390/nu13124523.
3
Iodine Intake for Pregnant and Breastfeeding Women and Their Infants Remains a Global Concern.孕妇、哺乳期妇女及其婴儿的碘摄入量仍然是一个全球关注的问题。
J Nutr. 2021 Dec 3;151(12):3604-3605. doi: 10.1093/jn/nxab364.
4
Iodine Nutrition and Iodine Supplement Initiation in Association with Thyroid Function in Mildly-to-Moderately Iodine-Deficient Pregnant and Postpartum Women.碘营养与甲状腺功能在轻度至中度碘缺乏的妊娠和产后妇女中补碘的关系。
J Nutr. 2021 Oct 1;151(10):3187-3196. doi: 10.1093/jn/nxab224.
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Clinically diagnosed iron and iodine deficiencies and disorders in the entire population of US military service members from 1997 to 2015.1997 年至 2015 年,美国全体军人中临床诊断的铁和碘缺乏及相关疾病。
Public Health Nutr. 2021 Aug;24(11):3187-3195. doi: 10.1017/S1368980021000495. Epub 2021 Feb 5.
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Intake and adequacy of the vegan diet. A systematic review of the evidence.素食饮食的摄入和充足性。证据的系统评价。
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Am J Obstet Gynecol. 2021 Jan;224(1):82.e1-82.e8. doi: 10.1016/j.ajog.2020.06.052. Epub 2020 Jul 9.
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Vegans, Vegetarians, and Omnivores: How Does Dietary Choice Influence Iodine Intake? A Systematic Review.素食者、素食者和杂食者:饮食选择如何影响碘摄入量?系统评价。
Nutrients. 2020 May 29;12(6):1606. doi: 10.3390/nu12061606.
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Feed-derived iodine overrides environmental contribution to cow milk.饲料来源的碘超过环境对牛奶的贡献。
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