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压力控制通气中的机械功率:一种简单可靠的床边方法。

Mechanical Power in Pressure-Controlled Ventilation: A Simple and Reliable Bedside Method.

作者信息

Snoep Jacob W M, Rietveld Petra J, van der Velde-Quist Franciska, de Jonge Evert, Schoe Abraham

机构信息

All authors: Department of Intensive Care, Leiden University Medical Center, Leiden, The Netherlands.

出版信息

Crit Care Explor. 2025 Mar 3;7(3):e1224. doi: 10.1097/CCE.0000000000001224. eCollection 2025 Mar 1.

Abstract

BACKGROUND

Mechanical power (MP) represents the amount of energy applied by the ventilator to the respiratory system over time. There are two main methods to calculate MP in mechanical ventilation. The first is the geometric method, which directly measures the dynamic inspiratory area of the pressure-volume loop during the respiratory cycle. The second involves using various algebraic equations to estimate MP. However, almost all calculations are either complex or not reliable compared with the geometric method, considered the gold standard. This study aimed to develop an easy to use, reliable equation for bedside calculation of MP and to compare its accuracy with other existing equations for calculating MP.

METHODS

In a preliminary study, we measured MP in 56 cases who were mechanically ventilated and without spontaneous breathing efforts. The measurements were done at the ICU of a single university medical center in the Netherlands.

RESULTS

We found that the MP can be accurately calculated using an equation that incorporates the plateau pressure in 56 cases in 42 patients. The MP estimated with our new proposed equation (MP calculated using plateau pressure) correlated well with the reference value of MP with a bias of 0.2 J/min. The 95% limits of agreement (LoAs) were -3.1 to + 3.4 J/min. Other equations give the following bias and LoAs; bias of -0.8, LoA -3.8 to 1.9 J/min (van der Meijden equation), bias of -1.9, LoA -3.7 to -0.0 J/min (comprehensive Becher equation), bias of -2.4, LoA -4.5 to -0.3 J/min (simplified Becher equation), and a bias of -1.9, LoA -3.7 to 0.1 J/min (linear model equation).

CONCLUSIONS

The equation we propose to calculate MP in pressure-controlled ventilation is a reliable, simple, and accurate alternative for the previously published equations. Consequently, this method is highly suitable for routine use in clinical practice.

摘要

背景

机械功率(MP)表示呼吸机在一段时间内施加于呼吸系统的能量。在机械通气中计算MP有两种主要方法。第一种是几何法,它直接测量呼吸周期中压力 - 容积环的动态吸气面积。第二种方法涉及使用各种代数方程来估算MP。然而,与被视为金标准的几何法相比,几乎所有计算要么复杂,要么不可靠。本研究旨在开发一种便于床边计算MP的易用、可靠方程,并将其准确性与其他现有的MP计算方程进行比较。

方法

在一项初步研究中,我们测量了56例接受机械通气且无自主呼吸努力患者的MP。测量在荷兰一所大学医学中心的重症监护病房进行。

结果

我们发现,在42例患者的56例病例中,使用包含平台压的方程可以准确计算MP。用我们新提出的方程(使用平台压计算的MP)估算的MP与MP参考值相关性良好,偏差为0.2 J/min。95%一致性界限(LoA)为 - 3.1至 + 3.4 J/min。其他方程给出的偏差和LoA如下:偏差为 - 0.8,LoA为 - 3.8至1.9 J/min(范德梅伊登方程),偏差为 - 1.9,LoA为 - 3.7至 - 0.0 J/min(综合贝歇尔方程),偏差为 - 2.4,LoA为 - 4.5至 - 0.3 J/min(简化贝歇尔方程),以及偏差为 - 1.9,LoA为 - 3.7至0.1 J/min(线性模型方程)。

结论

我们提出的用于压力控制通气中计算MP的方程是先前发表方程的一种可靠、简单且准确的替代方法。因此,该方法非常适合在临床实践中常规使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04a2/11878992/921533f03146/cc9-7-e1224-g001.jpg

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