Hang Tran K L, Tian Fangyuan
Department of Chemistry and Biochemistry, California State University Long Beach, Long Beach, CA, USA.
Methods Mol Biol. 2025;2902:1-12. doi: 10.1007/978-1-0716-4402-7_1.
Selective metal-organic frameworks (MOFs) have been studied as promising candidates for biomedical applications, especially as drug delivery systems due to their exceptional structural properties. This work reports the detailed methods to prepare an iron-containing MOF, MIL-88B(Fe), on functionalized gold and medical-grade stainless steel surfaces for drug delivery. We present a general procedure for preparing a novel drug carrier that can potentially be used as drug-eluting stent coatings.
选择性金属有机框架（MOF）已被研究作为生物医学应用中有前景的候选材料，特别是由于其优异的结构特性而作为药物递送系统。这项工作报告了在功能化金和医用级不锈钢表面制备用于药物递送的含铁MOF即MIL-88B(Fe)的详细方法。我们提出了一种制备新型药物载体的通用程序，该载体有可能用作药物洗脱支架涂层。
