Hajebi Ahmad, Hajiabadi Ilia Zamani, Fendereski Afsaneh, Ghodssighassemabadi Robabeh, Zamani Hajiabadi Arshia, Hosseini Jalil, Samadaee Gelehkolaee Keshvar
Research Center for Addiction & Risky Behaviors (ReCARB), Psychosocial Health Research Institute, Iran University of Medical Sciences, Tehran, Iran.
Department of Psychiatry, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran.
BMC Psychiatry. 2025 Mar 3;25(1):189. doi: 10.1186/s12888-025-06616-7.
Major depressive disorder (MDD) is one of the health problems that imposes a large disease burden on the community. Its prevalence is based on gender. Therefore, this study aims to investigate the prevalence of MDD in Iranian men between 2011 and 2022.
The Medline, Embase, Scopus, Web of Sciences, PsycINfo, and Iranian databases were searched for studies published from January 2011 to December 2022. Two independent reviewers screened the observational studies conducted on men aged 15 years and older with MDD. The interested outcomes were the prevalence type of MDD.
Data of 5 studies were included in the present meta-analysis. Among 10,667 participants in the study, 1479 (13.9%) individuals had a history of MDD. In the subgroup analysis, the average lifetime prevalence was 7.6% (95% confidence interval [CI]; 4.7 - 12.0%) and the point prevalence was 19.1% (95% confidence interval [CI]; 6.7 - 43.5%) based on random effect model. The 12-month prevalence was 10.8% (95% confidence interval [CI]; 9.8 - 11.9%) based on the single study.
Preventive and therapeutic programs are strongly recommended due to the high prevalence of major depression in Iranian men and the lack of sufficient studies in this field.
重度抑郁症（MDD）是给社区带来巨大疾病负担的健康问题之一。其患病率因性别而异。因此，本研究旨在调查2011年至2022年伊朗男性中重度抑郁症的患病率。
检索了Medline、Embase、Scopus、科学网、PsycINfo和伊朗数据库中2011年1月至2022年12月发表的研究。两名独立评审员筛选了针对15岁及以上患有重度抑郁症男性进行的观察性研究。感兴趣的结果是重度抑郁症的患病率类型。
本荟萃分析纳入了5项研究的数据。在该研究的10667名参与者中，1479人（13.9%）有重度抑郁症病史。在亚组分析中，基于随机效应模型，平均终生患病率为7.6%（95%置信区间[CI]；4.7 - 12.0%），时点患病率为19.1%（95%置信区间[CI]；6.7 - 43.5%）。基于单项研究，12个月患病率为10.8%（95%置信区间[CI]；9.8 - 11.9%）。
鉴于伊朗男性中重度抑郁症的高患病率以及该领域缺乏足够的研究，强烈建议开展预防和治疗项目。
