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基于医学数字成像和通信(DICOM)数据开发用于医学教育和研究应用的3D打印Wistar大鼠模型。

Development of a 3D-Printed Wistar Rat Model From Digital Imaging and Communications in Medicine (DICOM) Data for Medical Education and Research Applications.

作者信息

Bogdanov Todor G, Hikov Todor A, Sabit Zafer A, Tafradzhiyska-Hadzhiolova Radka, Pencheva Daliya T

机构信息

Medical Physics and Biophysics, Medical University - Sofia, Sofia, BGR.

Physiology and Pathophysiology, Medical University - Sofia, Sofia, BGR.

出版信息

Cureus. 2025 Jan 26;17(1):e78012. doi: 10.7759/cureus.78012. eCollection 2025 Jan.

Abstract

Three-dimensional (3D) printing has revolutionized medical education and research by enabling the creation of accurate anatomical models derived from imaging studies. This report details the development of a 3D-printed Wistar rat model, produced using DICOM (Digital Imaging and Communications in Medicine) data from a single radiological study. The model was designed to serve as an educational tool for medical and veterinary students and as a resource for researchers. DICOM data from a single animal study was segmented and converted into a high-resolution 3D model using specialized software that converts the voxels from the slices into a waterfall volume with a uniform surface. The resulting STL file underwent optimization to ensure compatibility with common 3D printing technologies, such as fused deposition modeling (FDM) and stereolithography (SLA). The final printed model replicates the intricate anatomical details of the Wistar rat, providing a valuable aid for studying rodent anatomy and simulating procedures in preclinical research. The STL file is freely accessible to researchers and educators, promoting the adoption of 3D-printed models in academic settings. Providing open access to this model, we aim to enable researchers, educators, and clinicians worldwide to utilize it for various purposes, including comparative anatomy studies, surgical training, and educational demonstrations. This approach significantly enhances the usability of our findings and fosters collaboration across disciplines, making the model a valuable resource for the scientific community. By integrating advanced imaging techniques with 3D printing, this study demonstrates a cost-effective and scalable approach to enhancing medical education and research capabilities.

摘要

三维(3D)打印通过利用成像研究生成精确的解剖模型,彻底改变了医学教育和研究。本报告详细介绍了一种3D打印的Wistar大鼠模型的开发过程,该模型使用来自单一放射学研究的DICOM(医学数字成像和通信)数据制作而成。该模型旨在作为医学和兽医专业学生的教育工具以及研究人员的资源。来自单一动物研究的DICOM数据经过分割,并使用专门软件转换为高分辨率3D模型,该软件将切片中的体素转换为具有均匀表面的瀑布状体积。生成的STL文件经过优化,以确保与常见的3D打印技术兼容,如熔融沉积建模(FDM)和立体光刻(SLA)。最终打印的模型复制了Wistar大鼠复杂的解剖细节,为研究啮齿动物解剖结构和模拟临床前研究中的操作提供了宝贵的帮助。研究人员和教育工作者可免费获取该STL文件,促进了学术环境中3D打印模型的采用。通过提供对该模型的开放访问,我们旨在使全球的研究人员、教育工作者和临床医生能够将其用于各种目的,包括比较解剖学研究、手术培训和教育演示。这种方法显著提高了我们研究结果的可用性,并促进了跨学科合作,使该模型成为科学界的宝贵资源。通过将先进的成像技术与3D打印相结合,本研究展示了一种经济高效且可扩展的方法来增强医学教育和研究能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f256/11875216/4c37604d3a85/cureus-0017-00000078012-i01.jpg

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