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小脑软化的自然史、治疗及预后(作者译)

[Natural history, treatment and outcome of cerebellar softening (author's transl)].

作者信息

Spinnler H, Sterzi R, Vallar G

出版信息

Riv Patol Nerv Ment. 1979 Nov-Dec;100(6):309-28.

PMID:400367
Abstract

21 adults with acute cerebellar softening were divided into two groups. In the first group (6 patients) the clinical course was progressive with deterioration of consciousness, signs of brain-stem compression and some degree of enlargement of ventricles (CT scan). Of these patients, three were treated surgically with success, one recovered spontaneously and two others died post-operatively. In the second group (15 patients) the course was much more favourable. Without surgery the cerebellar symptoms and signs improved, in spite of the persistence of discrete cerebellar signs one month after the onset of symptoms. Medical and/or surgical treatment of the disease are discussed, including the differential diagnostic aspects as well as the CT scan features.

摘要

21例急性小脑软化成人患者被分为两组。第一组(6例患者)临床病程呈进行性,伴有意识障碍、脑干受压体征及脑室一定程度扩大(CT扫描显示)。这些患者中,3例接受手术治疗且成功,1例自发恢复,另外2例术后死亡。第二组(15例患者)病程则更为乐观。尽管症状出现1个月后仍存在轻微小脑体征,但未经手术小脑症状和体征仍有所改善。本文讨论了该疾病的药物和/或手术治疗,包括鉴别诊断方面以及CT扫描特征。

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