White John A, Dukers-Muijrers Nicole Htm, Hoebe Christian Jpa, Kenyon Chris R, Dc Ross Jonathan, Unemo Magnus
Northern and Western Health & Social Care Trusts, Londonderry, UK.
Department of Health Promotion, Care and Public Health Research Institute (CAPHRI), Maastricht University, Maastricht, the Netherlands.
Int J STD AIDS. 2025 May;36(6):434-449. doi: 10.1177/09564624251323678. Epub 2025 Mar 4.
Sexually transmitted infections remain common globally and most frequently are asymptomatic. The 2025 European guideline provides up-to-date guidance regarding indications for testing and treatment of infections. It includes advice on urogenital and extragenital testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for infections is also discussed.
性传播感染在全球范围内仍然很常见，而且大多数情况下是无症状的。2025年欧洲指南提供了关于感染检测和治疗指征的最新指导。它包括关于泌尿生殖系统和生殖器外检测的建议，包括使用自行采集的标本；建议仅使用经过验证的核酸扩增检测（NAATs）进行诊断；以及建议优先使用多西环素作为一线药物治疗所有感染，而不是单剂量阿奇霉素方案。还讨论了在无症状人群中进行广泛筛查以检测感染的证据不足和价值有限的问题。
