Jamil Safayet, Hossain Md Jamal, Mohammad Ali Habib, Akon Md Rakib, Asumah Mubarick Nungbaso, Hasan Mahdi, Suresh Harshini, Okesanya Olalekan John, Al-Mamun Md, Ahmed Mohamed Mustaf, Sarkar Tanzeema Younus, Sarker Md Fouad Hossain
Department of Public Health Daffodil International University Birulia Bangladesh.
Department of Public and Community Health Faculty of Medicine and Health Sciences Frontier University Garowe Puntland Somalia.
Health Sci Rep. 2025 Mar 3;8(3):e70526. doi: 10.1002/hsr2.70526. eCollection 2025 Mar.
Antibiotic resistance is increasing globally and regionally, posing a significant public health concern. This study aimed to assess knowledge and attitude toward antibiotic use and the prevalence of self-medication and its association with the knowledge and attitude toward antibiotic use and resistance among private university teachers in Bangladesh.
This quantitative, cross-sectional study utilized a convenience sampling technique and included 509 respondents. All data were collected using both face-to-face and online versions. Data were collected through both face-to-face and online surveys with all questions in a closed-ended format. Data analysis was conducted using IBM SPSS (version 20), employing frequency analysis, chi-squared tests, and logistic regression.
Among the respondents, 47.9% demonstrated high knowledge of antibiotic use and resistance. Only 19.3% showed a strong positive attitude toward antibiotic use and resistance. Self-medication with antibiotics was reported by 29.0% of respondents. Logistic regression analysis revealed that female participants were 5.02 times more knowledgeable about antibiotic use and resistance than male participants (95% CI: 2.72-9.91; < 0.001). Additionally, respondents over 40 years old had a 3.71 times higher attitude toward antibiotic use and resistance than those aged 30 or below (95% CI: 1.98-7.06; < 0.001). Females were 6.79 times more likely to self-medicate with antibiotics compared to males (95% CI: 3.67-13.43), and respondents aged 31-40 were 3.91 times more likely to practice self-medication than other age groups (95% CI: 1.07-3.86). Furthermore, participants with low knowledge and a low attitude toward antibiotic use and resistance were 3.87 times and 4.26 times more likely to self-meditate, respectively, than those who had high knowledge and attitude scores (95% CI: 2.00-5.70 and 95% CI: 1.99-5.12).
To combat antibiotic resistance, campaigns and seminars on responsible antibiotic use should be held at university level. Additionally, enforcement of laws prohibiting unnecessary antibiotic sales in retail pharmacies is essential.
抗生素耐药性在全球和地区范围内不断增加，引发了重大的公共卫生问题。本研究旨在评估孟加拉国私立大学教师对抗生素使用的知识和态度、自我药疗的流行情况及其与抗生素使用和耐药性知识与态度的关联。
本定量横断面研究采用便利抽样技术，纳入了509名受访者。所有数据通过面对面和在线两种版本收集。通过面对面和在线调查收集数据，所有问题均为封闭式。使用IBM SPSS（版本20）进行数据分析，采用频率分析、卡方检验和逻辑回归。
在受访者中，47.9%对抗生素使用和耐药性有较高的了解。只有19.3%对抗生素使用和耐药性表现出强烈的积极态度。29.0%的受访者报告有使用抗生素自我药疗的情况。逻辑回归分析显示，女性参与者对抗生素使用和耐药性了解的可能性是男性参与者的5.02倍（95%置信区间：2.72 - 9.91；P < 0.001）。此外，40岁以上的受访者对抗生素使用和耐药性的态度比30岁及以下的受访者高3.71倍（95%置信区间：1.98 - 7.06；P < 0.001）。女性使用抗生素自我药疗的可能性是男性的6.79倍（95%置信区间：3.67 - 13.43），31 - 40岁的受访者进行自我药疗的可能性是其他年龄组的3.91倍（95%置信区间：1.07 - 3.86）。此外，对抗生素使用和耐药性知识和态度较低的参与者自我药疗的可能性分别是知识和态度得分较高者的3.87倍和4.26倍（95%置信区间：2.00 - 5.70和95%置信区间：1.99 - 5.12）。
为应对抗生素耐药性，应在大学层面开展关于合理使用抗生素的宣传活动和研讨会。此外，执行禁止零售药店不必要销售抗生素的法律至关重要。
