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每日一次使用头孢曲松治疗皮肤和软组织感染。

Once-daily ceftriaxone for skin and soft tissue infections.

作者信息

Gordin F M, Wofsy C B, Mills J

出版信息

Antimicrob Agents Chemother. 1985 Apr;27(4):648-9. doi: 10.1128/AAC.27.4.648.

DOI:10.1128/AAC.27.4.648
PMID:4004197
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC180114/
Abstract

We prospectively compared once-daily administration of ceftriaxone with cefazolin given every 8 h for the treatment of skin and soft tissue infections. Thirty-one patients received cefazolin for a mean of 4.5 days, and 26 patients received ceftriaxone for a mean of 4.0 days. All patients had a satisfactory response. Adverse reactions were few and reversible. Ceftriaxone given as a single daily intramuscular injection is effective therapy for skin and soft tissue infections.

摘要

我们前瞻性地比较了每日一次给予头孢曲松与每8小时给予头孢唑林治疗皮肤和软组织感染的疗效。31例患者接受头孢唑林治疗，平均疗程为4.5天，26例患者接受头孢曲松治疗，平均疗程为4.0天。所有患者均有满意的疗效。不良反应少且可逆。每日一次肌内注射头孢曲松是治疗皮肤和软组织感染的有效疗法。

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本文引用的文献

1
Cost comparisons among antimicrobial agents.抗菌药物之间的成本比较。
N Engl J Med. 1982 Sep 9;307(11):689. doi: 10.1056/NEJM198209093071120.
2
Intravenous antibiotic therapy in an outpatient setting.门诊环境下的静脉抗生素治疗。
JAMA. 1982 Jul 16;248(3):336-9.
3
Antibacterial activity of ceftriaxone (Ro 13-9904), a beta-lactamase-stable cephalosporin.头孢曲松（Ro 13 - 9904）的抗菌活性，一种对β-内酰胺酶稳定的头孢菌素。
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Home intravenous antibiotic therapy: a team approach.家庭静脉抗生素治疗：团队协作方法
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Ceftizoxime compared with cefamandole for treatment of soft tissue infections.
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Efficacy of a twelve-hourly ceftriaxone regimen in the treatment of serious bacterial infections.每12小时一次头孢曲松治疗方案对严重细菌感染的疗效。
Antimicrob Agents Chemother. 1982 Jul;22(1):103-7. doi: 10.1128/AAC.22.1.103.
7
Pharmacokinetics and tolerance of ceftriaxone in humans after single-dose intramuscular administration in water and lidocaine diluents.头孢曲松在水中和利多卡因稀释剂中单剂量肌内注射后在人体中的药代动力学和耐受性。
Antimicrob Agents Chemother. 1982 Jun;21(6):957-62. doi: 10.1128/AAC.21.6.957.
8
Comparative in vitro studies of Ro 13-9904, a new cephalosporin derivative.新型头孢菌素衍生物Ro 13-9904的体外比较研究
Antimicrob Agents Chemother. 1981 Mar;19(3):435-42. doi: 10.1128/AAC.19.3.435.
9
Skin and soft tissue polymicrobial infections from intravenous abuse of drugs.静脉注射毒品所致皮肤及软组织混合感染
West J Med. 1979 Mar;130(3):200-4.