Rochiccioli P, Tock Mine Y Y, Enjaume C, Dutau G, Sablayrolles B
Arch Fr Pediatr. 1985 Apr;42(4):273-6.
Final heights were studied in 54 children followed for several years for growth retardation with delayed puberty. At the time of the first visit (13 9/12 in boys, 11 10/12 +/- 13/12 in girls), growth retardation was -2.7 +/- 0.8 in boys and -2.8 +/- 0.8 SD in girls. Retardation of bone age with respect to chronological age was always significant (2 7/12 +/- 10/12 yrs in boys and 2 7/12 +/- 9/12 in girls). Catch-up, calculated in terms of standard deviation score (SDS) between the first visit score and the final height was established for each child, as was the prognosis of height according to 3 methods (Bayley, Tanner, Roche). There is a highly significant correlation (r = 0.49; p less than 0.001) between the ratio of delayed bone age/chronological age (BA/CA) and the height catch-up calculated in SDS. On the contrary there is no correlation between the ratio BA/CA and the final height. This lack of correlation may be explained by the role taken by others factors, especially the parents heights, as a significant correlation was found between the final heights, the fathers heights (r = 0.29) and the mothers heights (r = 0.36). Thus, delayed bone maturation may be considered as a favourable factor for the prognosis of adult height.
对54名因青春期延迟而生长发育迟缓并随访数年的儿童的最终身高进行了研究。首次就诊时(男孩为13又9/12岁,女孩为11又10/12 ± 13/12岁),男孩的生长迟缓为 -2.7 ± 0.8,女孩为 -2.8 ± 0.8标准差。骨龄相对于实际年龄的延迟始终显著(男孩为2又7/12 ± 10/12岁,女孩为2又7/12 ± 9/12岁)。为每个孩子计算了首次就诊分数与最终身高之间以标准差分数(SDS)表示的追赶情况,以及根据三种方法(贝利、坦纳、罗氏)得出的身高预后情况。延迟骨龄/实际年龄之比(BA/CA)与以SDS计算的身高追赶之间存在高度显著的相关性(r = 0.49;p < 0.001)。相反,BA/CA之比与最终身高之间没有相关性。这种缺乏相关性可能是由其他因素的作用所解释的,尤其是父母的身高,因为在最终身高、父亲身高(r = 0.29)和母亲身高(r = 0.36)之间发现了显著的相关性。因此,骨成熟延迟可被视为成人身高预后的一个有利因素。