Johnson D K, Balmaseda M T
Arch Phys Med Rehabil. 1985 Jun;66(6):394-6.
Pseudomembranous colitis is a well-known disease associated with antibiotic administration and caused by the Clostridium difficile toxin. Clinical presentation is usually marked by watery diarrhea, crampy abdominal pain, and fever. Since early appropriate therapy can reduce morbidity and mortality, it is important for health care professionals to be aware of this disease. Patients with spinal cord injury have a relatively high incidence of respiratory and urinary tract infections that are treated with antibiotics. Therefore, these patients theoretically have a higher risk of contracting pseudomembranous colitis. This article presents a case report of a spinal cord injured patient with this disease who has several of the common difficulties encountered in the diagnosis and treatment, such as indeterminate assays and relapses. The clinical presentation, diagnosis, and treatment of pseudomembranous colitis are described.
伪膜性结肠炎是一种与抗生素使用相关的知名疾病，由艰难梭菌毒素引起。临床表现通常以水样腹泻、痉挛性腹痛和发热为特征。由于早期适当治疗可降低发病率和死亡率，因此医疗保健专业人员了解这种疾病很重要。脊髓损伤患者呼吸道和泌尿道感染的发生率相对较高，需要使用抗生素治疗。因此，这些患者理论上患伪膜性结肠炎的风险更高。本文介绍了一例患有这种疾病的脊髓损伤患者的病例报告，该患者在诊断和治疗过程中遇到了一些常见困难，如检测结果不确定和复发。文中描述了伪膜性结肠炎的临床表现、诊断和治疗。
