Kishan Karkala Venkappa, Shah Nimisha, Mamatha Karkala Venkappa, Sreekumari Lekshmipriya, Parikh Margi
Department of Conservative Dentistry and Endodontics, Srinivas Dental College and Hospital, Mangalore, Karnataka, India.
Department of Conservative Dentistry and Endodontics, K. M. Shah Dental College, Sumandeep Vidyapeeth, Vadodara, Gujarat, India.
J Conserv Dent Endod. 2025 Feb;28(2):155-160. doi: 10.4103/JCDE.JCDE_824_24. Epub 2025 Feb 3.
The purpose of the study was to clinically evaluate interappointment flare-ups, on placing (neem), garlic ( L.), Triphala, and calcium hydroxide (CH) as an intracanal medicament (ICM), using Verbal Rating Scale (VRS) in a patient with a primary endodontic lesion.
Two hundred and forty patients indicated for root canal therapy were divided into two main groups as single-rooted teeth and multirooted teeth. Each group was further subdivided into four subgroups of 30 samples each. After the access opening, instrumentation was done as per the canal configuration. The herbal medicaments were prepared as an aqueous extract. The placement of ICM in the subgroups was randomly determined by computerized randomization. Interappointment flare-up and pain were assessed using VRS on 1, 3, 7, and 14 days.
The intergroup comparisons of the incidence of flare-up were done using analysis of variance, followed by Tukey's test to test for the difference among individual groups.
There was a statistically significant difference between the four groups, with = 0.02 for multirooted teeth and 0.03 for single-rooted teeth. The Tukey's test showed the intergroup comparison of the flare-up incidence between garlic and Triphala to be statistically significant favoring Triphala, with = 0.004 in single-rooted teeth and 0.008 in multirooted teeth.
Although there was no statistical significance between them, Triphala can be considered an alternative to CH as ICM. However, neem and garlic showed poor results.
本研究旨在对患有原发性牙髓病变的患者,使用言语评定量表(VRS),临床评估在根管内放置印楝(neem)、大蒜(garlic)、三果木(Triphala)和氢氧化钙(CH)作为根管内药物(ICM)期间的复诊间疼痛突发情况。
240例需要进行根管治疗的患者被分为两个主要组,即单根牙组和多根牙组。每组再进一步细分为四个亚组,每组30个样本。开髓后,根据根管形态进行根管预备。草药制剂制成水提取物。通过计算机随机化随机确定亚组中ICM的放置。在第1、3、7和14天使用VRS评估复诊间疼痛突发情况和疼痛程度。
使用方差分析进行突发情况发生率的组间比较,随后进行Tukey检验以检验各个组之间的差异。
四组之间存在统计学显著差异,多根牙组的P值为0.02,单根牙组的P值为0.03。Tukey检验显示大蒜和三果木之间突发情况发生率的组间比较具有统计学显著性,有利于三果木,单根牙组的P值为0.004,多根牙组的P值为0.008。
尽管它们之间没有统计学显著性,但三果木可被视为作为ICM替代CH的一种选择。然而,印楝和大蒜的效果较差。