Palomba Stefano, Seminara Giuseppe, Tomei Francesco, Marino Angelo, Morgante Giuseppe, Baldini Domenico, Papaleo Enrico, Ragusa Guglielmo, Aversa Antonio, Allegra Adolfo, Guglielmino Antonino, Somigliana Edgardo
Department of Medical-Surgical Science and Translational Medicine, Obstetrics & Gynecology, Sapienza University of Rome, Via Di Grottarossa 1039, Rome, Italy.
Department of Experimental and Clinical Medicine, University Magna Graecia of Catanzaro, Catanzaro, Italy.
Reprod Biol Endocrinol. 2025 Mar 8;23(1):37. doi: 10.1186/s12958-025-01372-5.
The polycystic ovary syndrome (PCOS) is a multifaced disease of the reproductive age associated with several comorbidities including infertility. Very few documents regarding the management of the infertility in women with PCOS, including guidelines, position papers and consensus conferences, are available in the literature. The Italian Law indicates that health professionals must comply with the recommendations set out in the guidelines developed by public and private bodies and institutions, as well as scientific societies and technical-scientific associations of the health professions, except for specific cases. Unfortunately, no guideline for the diagnosis and the management of infertility in women with PCOS is currently available in Italy. In 2024, the Italian Society of Human Reproduction (SIRU) and the Italian Centers for the Study and Conservation of Eggs and Sperm (CECOS Italy) pointed out the need to produce Italian guidelines on this topic and established a specific working group to develop those guidelines. The working group chose to adapt the guideline with highest quality to the Italian context rather than developing a de novo document. The International Evidence-Based Guideline for the Assessment and Management of PCOS guidelines were selected. All recommendations regarding the diagnosis and the management of women with PCOS and infertility extracted, adapted to the Italian context and improved incorporating new recommendations or practical comments and suggestions where needed.
多囊卵巢综合征（PCOS）是一种发生于育龄期的多面性疾病，与包括不孕症在内的多种合并症相关。文献中关于PCOS女性不孕症管理的文件，包括指南、立场文件和共识会议，非常少见。意大利法律规定，除特定情况外，卫生专业人员必须遵守公共和私人机构以及卫生专业的科学协会和技术科学协会制定的指南中提出的建议。不幸的是，目前意大利没有关于PCOS女性不孕症诊断和管理的指南。2024年，意大利人类生殖学会（SIRU）和意大利卵子与精子研究与保存中心（CECOS意大利）指出有必要制定关于这一主题的意大利指南，并成立了一个专门的工作组来制定这些指南。该工作组选择将质量最高的指南适用于意大利的情况，而不是重新制定一份文件。选择了《多囊卵巢综合征评估和管理国际循证指南》。提取了所有关于PCOS女性不孕症诊断和管理的建议，根据意大利的情况进行调整，并在需要时纳入新的建议或实际意见和建议进行完善。
