Tasnim Sadia, Raja Siva, Ramji Sadhvika, NeMoyer Rachel, Blackstone Eugene H, Toth Andrew J, Barron John O, Raymond Daniel P, Murthy Sudish C, Sudarshan Monisha
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio.
Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.
JTCVS Open. 2024 Oct 21;23:276-287. doi: 10.1016/j.xjon.2024.09.032. eCollection 2025 Feb.
The study objective was to assess adverse events, readmissions, and resource use associated with routine jejunostomy tube placement after esophagectomy.
From September 2018 to October 2021, 215 patients, with a median age of 65 years and a median body mass index of 27 kg/m, underwent routine jejunostomy tube placement during esophagectomy. J-tube-related adverse events were collected from date of surgery to date of removal and categorized as (1) nonserious, resource-nonintensive (eg, skin irritations, discomfort); (2) nonserious, resource-intensive (eg, infection, clogged, and dislodged tubes); and (3) serious, resource-intensive (eg, bowel obstruction, volvulus, tube feed intolerance). Esophagectomy and jejunostomy tube-related readmissions and nutritional markers were also assessed during the jejunostomy tube indwelling time.
Of the 215 patients, 177 experienced 459 events documented during 372 healthcare encounters. Nonserious adverse events occurred within 4 to 6 weeks after surgery with the peak at 3 to 4 weeks. Serious adverse events (4, 0.9%) were rare and occurred mostly in the acute postoperative period. Thirty-five patients (16%) were readmitted during their jejunostomy tube indwelling time, of whom 14 (7%) were readmitted due to jejunostomy tube-related issues. Jejunostomy tube-related events were not predictors for readmission. Nutritional status stabilized within 30 days of surgery.
Serious adverse events after routine jejunostomy tube placement postesophagectomy are rare and occur mostly in the immediate postoperative period. Nonserious adverse events are more common and can be resource-intensive, providing an opportunity for improvement. Readmissions for jejunostomy tube complications are low. Nutritional status is appropriately maintained with supplemental jejunostomy tube feeding postesophagectomy. These findings suggest that routine jejunostomy tube placement at the time of esophagectomy can be a reasonable management strategy as part of a delayed feeding algorithm.
本研究旨在评估食管癌切除术后常规空肠造口管置入相关的不良事件、再入院情况及资源利用情况。
2018年9月至2021年10月,215例患者在食管癌切除术中接受了常规空肠造口管置入,患者中位年龄65岁,中位体重指数为27kg/m。收集从手术日期至拔除日期与空肠造口管相关的不良事件,并分为以下几类:(1)非严重、资源消耗少的(如皮肤刺激、不适);(2)非严重、资源消耗多的(如感染、堵塞和移位的导管);(3)严重、资源消耗多的(如肠梗阻、肠扭转、管饲不耐受)。在空肠造口管留置期间,还评估了食管癌切除术和空肠造口管相关的再入院情况及营养指标。
215例患者中,177例在372次医疗接触期间发生了459起记录在案的事件。非严重不良事件发生在术后4至6周内,高峰出现在3至4周。严重不良事件(4例,0.9%)罕见,主要发生在术后急性期。35例患者(16%)在空肠造口管留置期间再次入院,其中14例(7%)因空肠造口管相关问题再次入院。空肠造口管相关事件不是再入院的预测因素。营养状况在手术后30天内稳定。
食管癌切除术后常规空肠造口管置入后的严重不良事件罕见,主要发生在术后即刻。非严重不良事件更常见,且可能资源消耗多,这提供了改进的机会。空肠造口管并发症导致的再入院率较低。食管癌切除术后通过空肠造口管补充喂养可适当维持营养状况。这些发现表明,食管癌切除时常规置入空肠造口管作为延迟喂养方案的一部分可能是一种合理的管理策略。